(R)-tert-butyl 4-(4-(benzyloxy)butyl)-2,2-diMethyloxazolidine-3-carboxylate

Base Information

• Chemical Name: (R)-tert-butyl 4-(4-(benzyloxy)butyl)-2,2-diMethyloxazolidine-3-carboxylate
• CAS No.: 1079209-05-4
• Molecular Formula: C21H33NO4
• Molecular Weight: 363.497
• Hs Code.: 2934999090
• Mol file: 1079209-05-4.mol

Synonyms:(R)-tert-butyl 4-(4-(benzyloxy)butyl)-2,2-diMethyloxazolidine-3-carboxylate

Chemical Property of (R)-tert-butyl 4-(4-(benzyloxy)butyl)-2,2-diMethyloxazolidine-3-carboxylate

Chemical Property:

• Boiling Point: 441.2±35.0 °C(Predicted)
• PKA: -1.53±0.60(Predicted)
• PSA: 48.00000
• Density: 1.036±0.06 g/cm3(Predicted)
• LogP: 4.68340
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(R)-tert-Butyl 4-(4-(benzyloxy)butyl)-2,2-dimethyloxazolidine-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-tert-butyl 4-(4-(benzyloxy)butyl)-2,2-diMethyloxazolidine-3-carboxylate

There total 1 articles about (R)-tert-butyl 4-(4-(benzyloxy)butyl)-2,2-diMethyloxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-tert-butyl 4-(4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate (1166394-91-7) + benzyl bromide (100-39-0) → tert-butyl (4S)-4-[4-(benzyloxy)butyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate (1079209-05-4)

Guidance literature:

(S)-tert-butyl 4-(4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate; With potassium tert-butylate; In tetrahydrofuran; at -12 ℃; Inert atmosphere;

benzyl bromide; In tetrahydrofuran; at -12 ℃;

Reference yield:

tert-butyl (4S)-4-[4-(benzyloxy)butyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate (1079209-05-4) → tert-butyl [(1S)-5-(benzyloxy)-1-(hydroxymethyl)pentyl]carbamate (1079209-06-5)

Guidance literature:

tert-butyl (4S)-4-[4-(benzyloxy)butyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate; With hydrogenchloride; In methanol; water; at 9 - 11.4 ℃; Inert atmosphere;

With sodium hydrogencarbonate; In water; toluene;

upstream raw materials:

(S)-tert-butyl 4-(4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate

benzyl bromide

Downstream raw materials:

tert-butyl [(1S)-5-(benzyloxy)-1-(hydroxymethyl)pentyl]carbamate

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