8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline

Base Information

Chemical Name:8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline
CAS No.:58509-59-4
Molecular Formula:C9H10N2O
Molecular Weight:162.191
Hs Code.:2933499090
Mol file:58509-59-4.mol

Synonyms:8(5H)-QUINOLINONE,6,7-DIHYDRO-,OXIME;6,7-dihydroquinolin-8(5H)-one oxime;6,7-dihydro-5H-quinolin-8-one oxime;8-(Hydroxyimino)-5,6,7,8-tetrahydrochinolin;QC-8556;(E)-6,7-dihydroquinolin-8(5H)-one oxime;S14-2758;6,7-dihydro-8(5H)-quinolinone oxime;

Suppliers and Price of 8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6,7-Dihydro-5H-quinolin-8-oneOxime
250mg
$ 180.00

TRC
6,7-Dihydro-5H-quinolin-8-oneOxime
500mg
$ 300.00

Chemcia Scientific
6,7-Dihydro-5H-quinolin-8-oneoxime ＞96%
0.5 G
$ 135.00

Chemcia Scientific
6,7-Dihydro-5H-quinolin-8-oneoxime ＞96%
1 G
$ 190.00

Apolloscientific
6,7-Dihydro-5h-quinolin-8-oneoxime 95%
250mg
$ 150.00

AK Scientific
(E)-6,7-Dihydroquinolin-8(5H)-oneoxime
5g
$ 1086.00

AccelPharmtech
6,7-dihydro-8(5H)-Quinolinoneoxime 97.00%
25G
$ 6710.00

AccelPharmtech
6,7-dihydro-8(5H)-Quinolinoneoxime 97.00%
5G
$ 3590.00

AccelPharmtech
6,7-dihydro-8(5H)-Quinolinoneoxime 97.00%
1G
$ 2100.00

Total 12 raw suppliers

Chemical Property of 8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline

Chemical Property:

Melting Point:173-175 °C(Solv: benzene (71-43-2))
Boiling Point:353.4±21.0 °C(Predicted)
PKA:10.37±0.20(Predicted)
PSA：45.48000
Density:1.27±0.1 g/cm3(Predicted)
LogP:1.59620
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

6,7-Dihydro-5H-quinolin-8-oneOxime ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 6,7-Dihydro-5H-quinolin-8-one Oxime is an intermediate; used in preparation of 3-heterocyclylacrylamide derivatives as FaBI protein inhibitors for treating bacterial infection.

Technology Process of 8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline

There total 4 articles about 8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 56826-69-8
5,6,7,8-tetrahydro-8-quinolinone

: 58509-59-4
6,7-dihydro-5H-quinolin-8-one oxime

Guidance literature:: With hydroxylamine hydrochloride; Inert atmosphere;
DOI:10.1039/c2gc35077g

Reference yield: 75.0%

: 10500-57-9
5,6,7,8-tetrahydroquinoline

: 58509-59-4
6,7-dihydro-5H-quinolin-8-one oxime

Guidance literature:: 5,6,7,8-tetrahydroquinoline; With n-butyllithium; lithium diisopropyl amide; In hexane; at -15 ℃;

With isopentyl nitrite; In hexane; at -15 ℃; for 1h;
DOI:10.1081/SCC-120024729

Reference yield:

: 28707-60-0
8-benzylidene-5,6,7,8-tetrahydroquinoline

: 58509-59-4
6,7-dihydro-5H-quinolin-8-one oxime

Guidance literature:: Multi-step reaction with 2 steps

1.1: ozone / methanol / 10 h / -78 °C

1.2: -78 - 20 °C

2.1: hydroxylamine hydrochloride / ethanol; water / 1 h / 110 °C

With hydroxylamine hydrochloride; ozone; In methanol; ethanol; water;