5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine
CAS No.:1172067-95-6
Molecular Formula:C7H4BrFN2
Molecular Weight:215.025
Hs Code.:2933399990
DSSTox Substance ID:DTXSID50696634
Wikidata:Q82626316
Mol file:1172067-95-6.mol

Synonyms:5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine;1172067-95-6;5-BROMO-4-FLUORO-7-AZAINDOLE;MFCD12031517;1H-PYRROLO[2,3-B]PYRIDINE, 5-BROMO-4-FLUORO-;SCHEMBL1468008;AMY9730;DTXSID50696634;PUJVSTYUTMVCSG-UHFFFAOYSA-N;AKOS015999086;PB16480;AS-33623;SY097900;CS-0004477;FT-0660556;A803735;5-bromanyl-4-fluoranyl-1H-pyrrolo[2,3-b]pyridine

Suppliers and Price of 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine
1g
$ 60.00

SynQuest Laboratories
5-Bromo-4-fluoro-7-azaindole
250 mg
$ 256.00

SynQuest Laboratories
5-Bromo-4-fluoro-7-azaindole
1 g
$ 704.00

Crysdot
5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine 95+%
1g
$ 755.00

Chemenu
5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine 95%+
1g
$ 1142.00

Apolloscientific
5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine 98%
250mg
$ 160.00

Apolloscientific
5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine 98%
1g
$ 440.00

American Custom Chemicals Corporation
5-BROMO-4-FLUORO-1H-PYRROLO[2,3-B]PYRIDINE 95.00%
5MG
$ 505.81

Alichem
5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine
1g
$ 958.80

Alichem
5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine
250mg
$ 402.32

Total 31 raw suppliers

Chemical Property of 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

Boiling Point:277.9±40.0 °C(Predicted)
PKA:5.00±0.20(Predicted)
PSA：28.68000
Density:1.90±0.1 g/cm3(Predicted)
LogP:2.46450
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:213.95419
Heavy Atom Count:11
Complexity:155

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC2=NC=C(C(=C21)F)Br

Technology Process of 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

There total 1 articles about 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 640735-23-5
4-fluoro-1H-pyrrolo[2,3-b]pyridine

: 1172067-95-6
5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C

1.2: 42 h / 20 °C

2.1: sec.-butyllithium / tetrahydrofuran; cyclohexane / 0.75 h / -78 °C / Inert atmosphere

2.2: 0.5 h / -78 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C

With tetrabutyl ammonium fluoride; sec.-butyllithium; sodium hydride; In tetrahydrofuran; cyclohexane; N,N-dimethyl-formamide; mineral oil;

Reference yield: 59.4%

: 1172067-95-6
5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

: 98-09-9
benzenesulfonyl chloride

: 1172067-98-9
5-bromo-4-fluoro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.333333h;

benzenesulfonyl chloride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

Reference yield:

: 1172067-95-6
5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

: 1172068-36-8
5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: nitric acid / 0.5 h / 0 °C

2: tin(II) chloride dihdyrate; hydrogenchloride / water / 1 h / 0 - 20 °C

With hydrogenchloride; tin(II) chloride dihdyrate; nitric acid; In water;