Acetamide, N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-

Base Information

Chemical Name:Acetamide, N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-
CAS No.:1196509-30-4
Molecular Formula:C9H7BrFN3O
Molecular Weight:272.0737832
Hs Code.:
Mol file:1196509-30-4.mol

Synonyms:N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetamide;AcetaMide, N-(5-broMo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-

Suppliers and Price of Acetamide, N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Acetamide, N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-

Chemical Property:

PSA：61.27000
LogP:3.07240

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Acetamide, N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-

There total 6 articles about Acetamide, N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1172068-36-8
5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-ylamine

: 64-19-7,77671-22-8
acetic acid

: 1196509-30-4
N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetamide

Guidance literature:: With triethylamine; In tetrahydrofuran; for 0.5h;

Reference yield:

: 1172067-95-6
5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

: 1196509-30-4
N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: nitric acid / 0.5 h / 0 °C

2.1: hydrogenchloride; tin(ll) chloride / 0 - 20 °C

2.2: pH 7

3.1: triethylamine / tetrahydrofuran / 0.5 h

With hydrogenchloride; nitric acid; triethylamine; tin(ll) chloride; In tetrahydrofuran;

Reference yield:

: 1172068-33-5
5-bromo-4-fluoro-3-nitro-1H-pyrrolo[2,3-b]pyridine

: 1196509-30-4
N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride; tin(ll) chloride / 0 - 20 °C

1.2: pH 7

2.1: triethylamine / tetrahydrofuran / 0.5 h

With hydrogenchloride; triethylamine; tin(ll) chloride; In tetrahydrofuran;