tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside

Base Information

• Chemical Name: tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside
• CAS No.: 142657-12-3
• Molecular Formula: C₄₉H₆₂O₁₂Si
• Molecular Weight: 871.11
• Mol file: 142657-12-3.mol

Synonyms:

Chemical Property of tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside

There total 6 articles about tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acetic anhydride (108-24-7) + tert-Butyldimethylsilyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-3-O-benzyl-β-D-xylopyranoside (142656-97-1) → tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside (142657-12-3)

Guidance literature:

With pyridine; for 12h; Ambient temperature;

Reference yield:

O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate (130177-78-5) → tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside (142657-12-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 percent / BF₃*OEt₂ / CH₂Cl₂ / 0.5 h / -25 °C

2: 95 percent / pyridine / 12 h / Ambient temperature

With pyridine; boron trifluoride diethyl etherate; In dichloromethane;

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → tert-Butyldimethylsilyl O-(2-O-Acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-2-O-acetyl-3-O-benzyl-β-D-xylopyranoside (142657-12-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 60 percent / imidazole / dimethylformamide / 2 h / -30 °C

2: 47 percent / BF₃*OEt₂ / CH₂Cl₂ / 0.5 h / -25 °C

3: 95 percent / pyridine / 12 h / Ambient temperature

With pyridine; 1H-imidazole; boron trifluoride diethyl etherate; In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

acetic anhydride

tert-Butyldimethylsilyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-3-O-benzyl-β-D-xylopyranoside

O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate

tert-butyldimethylsilyl chloride