2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide

Base Information

• Chemical Name: 2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide
• CAS No.: 1394856-63-3
• Molecular Formula: C₂₁H₂₁N₅OS
• Molecular Weight: 391.497
• Mol file: 1394856-63-3.mol

Synonyms:

Chemical Property of 2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide

There total 2 articles about 2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

m-tolyl aldehyde (620-23-5) → 2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide (1394856-63-3)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic anhydride; sodium acetate / Inert atmosphere; Microwave irradiation

2: sodium acetate; acetic acid / Microwave irradiation; Inert atmosphere

3: N,N-dimethyl-formamide / Inert atmosphere; Microwave irradiation

With sodium acetate; acetic anhydride; acetic acid; In N,N-dimethyl-formamide;

DOI:10.1007/s00044-012-0190-z

Reference yield:

4-(3-methylphenyl)methylene-2-methyl-5(4H)-oxazolone (78311-97-4) → 2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide (1394856-63-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate; acetic acid / Microwave irradiation; Inert atmosphere

2: N,N-dimethyl-formamide / Inert atmosphere; Microwave irradiation

With sodium acetate; acetic acid; In N,N-dimethyl-formamide;

DOI:10.1007/s00044-012-0190-z

Reference yield: 55.0%

2-(1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazinecarbothioamide (1394856-63-3) + ethyl bromoacetate (105-36-2) → 2-((1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazono)thiazolidin-4-one (1394856-78-0)

Guidance literature:

With sodium acetate; In N,N-dimethyl-formamide; for 0.116667h; Microwave irradiation; Inert atmosphere;

DOI:10.1007/s00044-012-0190-z

upstream raw materials:

m-tolyl aldehyde

4-(3-methylphenyl)methylene-2-methyl-5(4H)-oxazolone

Downstream raw materials:

2-((1-(4-(2-methyl-4-(3-methylbenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)phenyl)ethylidene)hydrazono)thiazolidin-4-one