1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1

Base Information

Chemical Name:1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1
CAS No.:917359-62-7
Molecular Formula:C₃₄H₂₉N₉
Molecular Weight:563.665
Hs Code.:

Synonyms:1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1;9-phenyl-8-[4-[[4-(3-pyridin-2-yl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]methyl]phenyl]-[1,2,4]triazolo[3,4-f][1,6]naphthyridine;1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1-piperidinyl]Methyl]phenyl]-

Suppliers and Price of 1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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American Custom Chemicals Corporation
9-PHENYL-8-[4-[[4-[5-(2-PYRIDINYL)-1H-1,2,4-TRIAZOL-3-YL]-1-PIPERIDINYL]METHYL]PHENYL]-1,2,4-TRIAZOLO-[3,4-F]-[1,6]-NAPHTHYRIDINE 95.00%
5MG
$ 505.45

Total 1 raw suppliers

Chemical Property of 1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1

Chemical Property:

PSA：100.78000
LogP:6.10910

Purity/Quality:: 9-PHENYL-8-[4-[[4-[5-(2-PYRIDINYL)-1H-1,2,4-TRIAZOL-3-YL]-1-PIPERIDINYL]METHYL]PHENYL]-1,2,4-TRIAZOLO-[3,4-F]-[1,6]-NAPHTHYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1

There total 19 articles about 1,2,4-Triazolo[3,4-f][1,6]naphthyridine, 9-phenyl-8-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 917363-81-6
(3-phenyl-2-{4-[4-(5-pyridin-2-yl-4H-[1,2,4]triazol-3-yl)-piperidin-1-ylmethyl]-phenyl}-[1,6]naphthyridin-5-yl)-hydrazine

: 149-73-5
trimethyl orthoformate

: 917359-62-7
9-phenyl-8-(4-{[4-(5-pyridin-2-yl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)[1,2,4]triazolo[3,4-f]-1,6-naphthyridine

Guidance literature:: In methanol; toluene; for 10h; Heating / reflux;

Reference yield:

: 234108-73-7
(2-chloro-pyridin-4-yl)-carbamic acid tert-butyl ester

: 917359-62-7
9-phenyl-8-(4-{[4-(5-pyridin-2-yl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)[1,2,4]triazolo[3,4-f]-1,6-naphthyridine

Guidance literature:: Multi-step reaction with 6 steps

1.1: tetrahydrofuran; N,N-dimethyl-formamide; pentane / 5 h / -70 - 20 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 20 °C / Heating / reflux

3.1: hydrogenchloride; water / 1,4-dioxane / 3 h / 0 - 20 °C

3.2: pH > 7

4.1: sodium tris(acetoxy)borohydride; acetic acid; triethylamine / 1-methyl-pyrrolidin-2-one / 20 °C

5.1: hydrazine / 1,4-dioxane / 0.08 h / 100 °C / Microwave reactor

6.1: methanol; toluene / 10 h / Heating / reflux

With hydrogenchloride; water; sodium tris(acetoxy)borohydride; acetic acid; triethylamine; lithium hexamethyldisilazane; hydrazine; In tetrahydrofuran; 1,4-dioxane; 1-methyl-pyrrolidin-2-one; methanol; N,N-dimethyl-formamide; toluene; pentane;

Reference yield:

: 14432-12-3
4-Amino-2-chloropyridine

: 917359-62-7
9-phenyl-8-(4-{[4-(5-pyridin-2-yl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)[1,2,4]triazolo[3,4-f]-1,6-naphthyridine

Guidance literature:: Multi-step reaction with 7 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 - 20 °C

2.1: tetrahydrofuran; N,N-dimethyl-formamide; pentane / 5 h / -70 - 20 °C

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 20 °C / Heating / reflux

4.1: hydrogenchloride; water / 1,4-dioxane / 3 h / 0 - 20 °C

4.2: pH > 7

5.1: sodium tris(acetoxy)borohydride; acetic acid; triethylamine / 1-methyl-pyrrolidin-2-one / 20 °C

6.1: hydrazine / 1,4-dioxane / 0.08 h / 100 °C / Microwave reactor

7.1: methanol; toluene / 10 h / Heating / reflux

With hydrogenchloride; water; sodium tris(acetoxy)borohydride; acetic acid; triethylamine; lithium hexamethyldisilazane; hydrazine; In tetrahydrofuran; 1,4-dioxane; 1-methyl-pyrrolidin-2-one; methanol; N,N-dimethyl-formamide; toluene; pentane;