(S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid

Base Information

Chemical Name:(S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid
CAS No.:132336-37-9
Molecular Formula:C15H18N3O7P
Molecular Weight:383.298
Hs Code.:2933599090
DSSTox Substance ID:DTXSID00456785
Wikidata:Q82279356
Mol file:132336-37-9.mol

Synonyms:132336-37-9;(S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid;[(2S)-1-(4-benzamido-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid;DTXSID00456785;OLNRVCCBVZSXBX-LBPRGKRZSA-N;A909331;({[(2S)-1-(4-benzamido-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid;(S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonicacid

Suppliers and Price of (S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonicacid 95+%
1g
$ 947.00

Chemenu
(S)-(((1-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonicacid 95%
1g
$ 893.00

American Custom Chemicals Corporation
(S)-(((1-(4-BENZAMIDO-2-OXOPYRIMIDIN-1(2H)-YL)-3-HYDROXYPROPAN-2-YL)OXY)METHYL)PHOSPHONIC ACID 95.00%
1G
$ 1904.70

American Custom Chemicals Corporation
(S)-(((1-(4-BENZAMIDO-2-OXOPYRIMIDIN-1(2H)-YL)-3-HYDROXYPROPAN-2-YL)OXY)METHYL)PHOSPHONIC ACID 95.00%
5MG
$ 500.69

Total 7 raw suppliers

Chemical Property of (S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid

Chemical Property:

PSA：160.79000
LogP:0.08130
Storage Temp.:2-8°C
XLogP3:-1.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:383.08823692
Heavy Atom Count:26
Complexity:625

Purity/Quality:

97% ^*data from raw suppliers

(S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)CC(CO)OCP(=O)(O)O
Isomeric SMILES:C1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)C[C@@H](CO)OCP(=O)(O)O

Technology Process of (S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid

There total 8 articles about (S)-(((1-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 132336-34-6
(S)-N₁-[2-hydroxy-3-(triphenylmethoxy)propyl]-N₄-benzoylcytosine

: 132336-37-9
N⁴-benzoyl-1-(S)-(3-hydroxy-2-phosphonomethoxypropyl)cytosine

Guidance literature:: With trimethylsilyl bromide; In acetonitrile;
DOI:10.1135/cccc19930649

Reference yield:

: 132336-36-8
diethyl (S)-4-N-benzoyl-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine

: 132336-37-9
N⁴-benzoyl-1-(S)-(3-hydroxy-2-phosphonomethoxypropyl)cytosine

Guidance literature:: With trimethylsilyl bromide; In dichloromethane; for 18h; Ambient temperature;
DOI:10.1016/S0040-4039(00)76875-4

Reference yield:

: 132336-35-7
[(S)-1-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-ylmethyl)-2-trityloxy-ethoxymethyl]-phosphonic acid diethyl ester

: 132336-37-9
N⁴-benzoyl-1-(S)-(3-hydroxy-2-phosphonomethoxypropyl)cytosine

Guidance literature:: Multi-step reaction with 2 steps

1: HCl(g) / CH₂Cl₂ / 0.17 h / 0 - 5 °C

2: TMSBr / CH₂Cl₂ / 18 h / Ambient temperature

With hydrogenchloride; trimethylsilyl bromide; In dichloromethane;
DOI:10.1016/S0040-4039(00)76875-4