Ethyl 3-(2,5-dimethoxyphenyl)-3-oxopropanoate

Base Information

Chemical Name:Ethyl 3-(2,5-dimethoxyphenyl)-3-oxopropanoate
CAS No.:60946-75-0
Molecular Formula:C13H16O5
Molecular Weight:252.267
Hs Code.:2918990090
DSSTox Substance ID:DTXSID30485780
Nikkaji Number:J184.141F
Wikidata:Q82325280
Mol file:60946-75-0.mol

Synonyms:Ethyl 3-(2,5-dimethoxyphenyl)-3-oxopropanoate;60946-75-0;ethyl 2',5'-dimethoxybenzoylacetate;3-( 2,5-dimethowy-phenyl)-3-oxo-propionic acid ethyl ester;Ethyl3-(2,5-dimethoxyphenyl)-3-oxopropanoate;SCHEMBL14936568;DTXSID30485780;SHLIKILXQQPHPF-UHFFFAOYSA-N;CS-0168620;FT-0720331

Suppliers and Price of Ethyl 3-(2,5-dimethoxyphenyl)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(2,5-dimethoxy-phenyl)-3-oxo-propionicacidethylester 95
10g
$ 2163.00

Crysdot
Ethyl3-(2,5-dimethoxyphenyl)-3-oxopropanoate 95+%
1g
$ 455.00

American Custom Chemicals Corporation
3-( 2,5-DIMETHOWY-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 95.00%
5MG
$ 498.01

Alichem
Ethyl3-(2,5-dimethoxyphenyl)-3-oxopropanoate
1g
$ 364.56

Acrotein
Ethyl3-(2,5-dimethoxyphenyl)-3-oxopropanoate 97%
0.5g
$ 247.50

Total 7 raw suppliers

Chemical Property of Ethyl 3-(2,5-dimethoxyphenyl)-3-oxopropanoate

Chemical Property:

PSA：61.83000
LogP:1.83970
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:252.09977361
Heavy Atom Count:18
Complexity:289

Purity/Quality:

98%Min ^*data from raw suppliers

3-(2,5-dimethoxy-phenyl)-3-oxo-propionicacidethylester 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C1=C(C=CC(=C1)OC)OC

Technology Process of Ethyl 3-(2,5-dimethoxyphenyl)-3-oxopropanoate

There total 4 articles about Ethyl 3-(2,5-dimethoxyphenyl)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1201-38-3
2',5'-dimethoxyacetophenone

: 105-58-8,76619-83-5
Diethyl carbonate

: 60946-75-0
ethyl 3-oxo-3-(2,5-dimethoxyphenyl)propionate

Guidance literature:: With sodium hydride; In toluene; mineral oil;
DOI:10.1016/j.bmc.2013.06.046

Reference yield: 68.0%

: 17918-14-8
2,5-dimethoxybenzoyl chloride

: 141-78-6
ethyl acetate

: 60946-75-0
ethyl 3-oxo-3-(2,5-dimethoxyphenyl)propionate

Guidance literature:: ethyl acetate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

2,5-dimethoxybenzoyl chloride; In tetrahydrofuran; for 0.666667h; Inert atmosphere;
DOI:10.1002/ejoc.201600178