1-Chloro-2-nitro-4-(phenylsulfonyl)benzene

Base Information

• Chemical Name: 1-Chloro-2-nitro-4-(phenylsulfonyl)benzene
• CAS No.: 4779-36-6
• Molecular Formula: C12H8ClNO4S
• Molecular Weight: 297.719
• Mol file: 4779-36-6.mol

Synonyms:6-Nitro-4-phenylsulfonylchlorobenzene;4-Chlor-3-nitro-diphenylsulfon;4-chloro-3-nitrophenyl phenyl sulphone;

Chemical Property of 1-Chloro-2-nitro-4-(phenylsulfonyl)benzene

Chemical Property:

• PSA: 88.34000
• LogP: 4.68500

Purity/Quality:

99% ^*data from raw suppliers

Benzene,1-chloro-2-nitro-4-(phenylsulfonyl)- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Chloro-2-nitro-4-(phenylsulfonyl)benzene

There total 9 articles about 1-Chloro-2-nitro-4-(phenylsulfonyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3-nitro-4-chlorosulfonyl chloride (97-08-5) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-nitro-4-(phenylsulfonyl)chlorobenzene (4779-36-6)

Guidance literature:

With aluminum (III) chloride; at 20 ℃; for 18h; Heating / reflux;

Reference yield:

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-nitro-4-(phenylsulfonyl)chlorobenzene (4779-36-6)

Guidance literature:

With aluminium trichloride;

DOI:10.1039/jr9360000218

Reference yield:

1-benzenesulfonyl-2,4-dinitro-benzene (896-80-0) → 2-nitro-4-(phenylsulfonyl)chlorobenzene (4779-36-6)

Guidance literature:

Multi-step reaction with 3 steps

1: ethylene glycol

2: aqueous methanol; ammonia / 130 °C

3: glacial acetic acid; concentrated H₂SO₄ / Diazotization_.Behandlung der Diazoniumsalz-Loesung mit CuCl in konz. wss. HCl

With methanol; sulfuric acid; ammonia; ethylene glycol; acetic acid;

DOI:10.1039/jr9360000218

upstream raw materials:

4-chlorobenzenesulfonyl chloride

benzene

1-benzenesulfonyl-2,4-dinitro-benzene

1,4-bis-benzenesulfonyl-2-nitro-benzene

Downstream raw materials:

4-benzenesulfonyl-1-methoxy-2-nitro-benzene

4-benzenesulfonyl-2-nitro-1-(toluene-4-sulfonyl)-benzene

1,4-bis-benzenesulfonyl-2-nitro-benzene

2-nitro-4-phenylsulfonylphenol