3',5'-Dimethyl-4'-methoxyacetophenone

Base Information

• Chemical Name: 3',5'-Dimethyl-4'-methoxyacetophenone
• CAS No.: 60609-65-6
• Molecular Formula: C11H14O2
• Molecular Weight: 178.231
• Hs Code.: 2914390090
• European Community (EC) Number: 675-410-1
• DSSTox Substance ID: DTXSID40374398
• Wikidata: Q82162973
• Mol file: 60609-65-6.mol

Synonyms:3',5'-Dimethyl-4'-methoxyacetophenone;60609-65-6;1-(4-methoxy-3,5-dimethylphenyl)ethanone;Ethanone, 1-(4-methoxy-3,5-dimethylphenyl)-;4'-Methoxy-3',5'-dimethylacetophenone;1-(4-methoxy-3,5-dimethylphenyl)ethan-1-one;SCHEMBL2796551;DTXSID40374398;CL8650;STK288942;AKOS000299288;FS-1702;CS-0313165;FT-0650904;1-(4-Methoxy-3,5-dimethyl-phenyl)-ethanone

Chemical Property of 3',5'-Dimethyl-4'-methoxyacetophenone

Chemical Property:

• Vapor Pressure: 0.00195mmHg at 25°C
• Melting Point: 47-48 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 291.4°C at 760 mmHg
• Flash Point: 126.5°C
• PSA: 26.30000
• Density: 1.004g/cm³
• LogP: 2.51460
• Storage Temp.: 2-8°C
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 178.099379685
• Heavy Atom Count: 13
• Complexity: 177

Purity/Quality:

97% ^*data from raw suppliers

3',5'-Dimethyl-4'-methoxyacetophenone 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1OC)C)C(=O)C

Technology Process of 3',5'-Dimethyl-4'-methoxyacetophenone

There total 7 articles about 3',5'-Dimethyl-4'-methoxyacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-(4-hydroxy-3,5-dimethylphenyl)ethanone (5325-04-2) + dimethyl sulfate (77-78-1) → 1-(4-methoxy-3,5-dimethylphenyl)ethanone (60609-65-6)

Guidance literature:

With potassium carbonate; In acetone; for 3h; Heating / reflux;

Reference yield: 70.0%

1-(4-hydroxy-3,5-dimethylphenyl)ethanone (5325-04-2) + methyl iodide (74-88-4) → 1-(4-methoxy-3,5-dimethylphenyl)ethanone (60609-65-6)

Guidance literature:

With potassium carbonate; In acetone;

DOI:10.1071/CH09517

Reference yield:

2-methoxy-1,3-dimethylbenzene (1004-66-6) + acetyl chloride (75-36-5) → 1-(4-methoxy-3,5-dimethylphenyl)ethanone (60609-65-6)

Guidance literature:

With aluminium trichloride; In benzene;

DOI:10.1016/S0040-4020(01)98632-6

upstream raw materials:

1-(4-hydroxy-3,5-dimethylphenyl)ethanone

dimethyl sulfate

2-methoxy-1,3-dimethylbenzene

acetyl chloride

Downstream raw materials:

N-(2,6-Dimethyl-phenyl)-N'-[1-(4-methoxy-3,5-dimethyl-phenyl)-eth-(E)-ylidene]-hydrazine

5-(4-methoxy-3,5-dimethylphenyl)-3H-1,2-dithiole-3-thione

5-ethyl-2-methoxy-1,3-dimethylbenzene

5-(3,5-dimethyl-4-methoxy-phenyl)-3H-1,2-dithiol-3-one