2H-Imidazole-2-thione, 1,3-dihydro-1-[2-(4-methoxyphenyl)ethyl]-

Base Information

Chemical Name:2H-Imidazole-2-thione, 1,3-dihydro-1-[2-(4-methoxyphenyl)ethyl]-
CAS No.:100134-69-8
Molecular Formula:C₁₂H₁₄N₂OS
Molecular Weight:234.322
Hs Code.:
DSSTox Substance ID:DTXSID00655579
Wikidata:Q82569769
ChEMBL ID:CHEMBL79689
Mol file:100134-69-8.mol

Synonyms:100134-69-8;CHEMBL79689;2H-Imidazole-2-thione, 1,3-dihydro-1-[2-(4-methoxyphenyl)ethyl]-;DTXSID00655579;1-[2-(4-Methoxyphenyl)ethyl]-1,3-dihydro-2H-imidazole-2-thione;BDBM50025488;1-[2-(4-Methoxy-phenyl)-ethyl]-1,3-dihydro-imidazole-2-thione

Suppliers and Price of 2H-Imidazole-2-thione, 1,3-dihydro-1-[2-(4-methoxyphenyl)ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-Imidazole-2-thione, 1,3-dihydro-1-[2-(4-methoxyphenyl)ethyl]-

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:234.08268425
Heavy Atom Count:16
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CCN2C=CNC2=S

Technology Process of 2H-Imidazole-2-thione, 1,3-dihydro-1-[2-(4-methoxyphenyl)ethyl]-

There total 5 articles about 2H-Imidazole-2-thione, 1,3-dihydro-1-[2-(4-methoxyphenyl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104-01-8
4-Methoxyphenylacetic acid

: 100134-69-8
1-(4-methoxy-phenethyl)-1,3-dihydro-imidazole-2-thione

Guidance literature:: Multi-step reaction with 4 steps

1: oxalyl chloride, pyridine / CH₂Cl₂ / 2.5 h

2: CH₂Cl₂ / 5 - 20 °C

3: LiAlH₄ / diethyl ether; tetrahydrofuran / 3.5 h / 22 °C

4: aq. 3 N HCl / ethanol / 5 h / Heating

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; oxalyl dichloride; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jm00162a008

Reference yield:

: N-(2,2-dimethoxyethyl)-2-(4-methoxyphenyl)acetamide

: 100134-69-8
1-(4-methoxy-phenethyl)-1,3-dihydro-imidazole-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether; tetrahydrofuran / 3.5 h / 22 °C

2: aq. 3 N HCl / ethanol / 5 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1021/jm00162a008

Reference yield:

: 4693-91-8
4-methoxyphenyl-acetic chloride

: 100134-69-8
1-(4-methoxy-phenethyl)-1,3-dihydro-imidazole-2-thione

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 5 - 20 °C

2: LiAlH₄ / diethyl ether; tetrahydrofuran / 3.5 h / 22 °C

3: aq. 3 N HCl / ethanol / 5 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jm00162a008