2-(3-(Benzyloxy)-4-methoxyphenyl)acetamide

Base Information

Chemical Name:2-(3-(Benzyloxy)-4-methoxyphenyl)acetamide
CAS No.:71146-77-5
Molecular Formula:C₁₆H₁₇NO₃
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID901262680

Synonyms:Benzeneacetamide, 4-methoxy-3-(phenylmethoxy)-;71146-77-5;DTXSID901262680;AKOS024322917;4-Methoxy-3-(phenylmethoxy)benzeneacetamide;2-(3-(Benzyloxy)-4-methoxyphenyl)acetamide;2-(3-BENZYLOXY-4-METHOXY-PHENYL)-ACETAMIDE;A1-40766

Suppliers and Price of 2-(3-(Benzyloxy)-4-methoxyphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-(3-(Benzyloxy)-4-methoxyphenyl)acetamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:302

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CC(=O)N)OCC2=CC=CC=C2

Technology Process of 2-(3-(Benzyloxy)-4-methoxyphenyl)acetamide

There total 5 articles about 2-(3-(Benzyloxy)-4-methoxyphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54313-33-6
2-(3-(benzyloxy)-4-methoxyphenyl)acetyl chloride

: 71146-77-5
2-(3-(benzyloxy)-4-methoxyphenyl)acetamide

Guidance literature:: With ammonia; In tetrahydrofuran; at 20 ℃; for 0.0833333h;
DOI:10.1002/jlcr.3206

Reference yield:

: 5487-33-2
O-benzylhomoisovanillic acid

: 71146-77-5
2-(3-(benzyloxy)-4-methoxyphenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 20 °C

2: ammonia / tetrahydrofuran / 0.08 h / 20 °C

With thionyl chloride; ammonia; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/jlcr.3206

Reference yield:

: 1131-94-8
homoisovanillic acid

: 71146-77-5
2-(3-(benzyloxy)-4-methoxyphenyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: tetra-n-butylphosphonium hydroxide / tetrahydrofuran / 3 h / 0 - 20 °C

2: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 20 °C

3: ammonia / tetrahydrofuran / 0.08 h / 20 °C

With thionyl chloride; ammonia; tetra-n-butylphosphonium hydroxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/jlcr.3206