(4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

Base Information

Chemical Name:(4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide
CAS No.:1391973-93-5
Molecular Formula:C₄₁H₆₇NO₉Si₂
Molecular Weight:774.155
Hs Code.:

(4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

Synonyms:

Suppliers and Price of (4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

There total 8 articles about (4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₉H₆₂O₉Si₂

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 1391973-93-5
(4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

Guidance literature:: C₃₉H₆₂O₉Si₂; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; Inert atmosphere;

N,O-dimethylhydroxylamine*hydrochloride; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1021/jo401706r

Reference yield:

: C₃₉H₆₂O₉Si₂

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 1391973-93-5
(4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

Guidance literature:: C₃₉H₆₂O₉Si₂; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; Inert atmosphere;

N,O-dimethylhydroxylamine*hydrochloride; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1021/jo401706r

Reference yield:

: methyl 5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-2,2-dimethyl-1,3-dioxolane-4-carboxylate

: 1391973-93-5
(4S,5R)-5-{[(2R,3S,4S,5R,6R)-4,5-bis(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-6-{[(tert-butyldimethylsilyl)oxy]methyl}oxan-2-yl]methyl}-N-methoxy-N,2,2-trimethyl-1,3-dioxolane-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: water; lithium hydroxide monohydrate / tetrahydrofuran / 0.58 h / 20 °C

2.1: 1,1'-carbonyldiimidazole / dichloromethane / 20 °C / Inert atmosphere

2.2: 4 h / 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; water; 1,1'-carbonyldiimidazole; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo401706r