Cyclobutanemethanol, 3,3-dimethoxy-, 1-(4-methylbenzenesulfonate)

Base Information

Chemical Name:Cyclobutanemethanol, 3,3-dimethoxy-, 1-(4-methylbenzenesulfonate)
CAS No.:175021-12-2
Molecular Formula:C₁₄H₂₀O₅S
Molecular Weight:300.376
Hs Code.:
DSSTox Substance ID:DTXSID001168413

Synonyms:DTXSID001168413;Cyclobutanemethanol, 3,3-dimethoxy-, 1-(4-methylbenzenesulfonate);175021-12-2

Suppliers and Price of Cyclobutanemethanol, 3,3-dimethoxy-, 1-(4-methylbenzenesulfonate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cyclobutanemethanol, 3,3-dimethoxy-, 1-(4-methylbenzenesulfonate)

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:300.10314491
Heavy Atom Count:20
Complexity:394

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCC2CC(C2)(OC)OC

Technology Process of Cyclobutanemethanol, 3,3-dimethoxy-, 1-(4-methylbenzenesulfonate)

There total 3 articles about Cyclobutanemethanol, 3,3-dimethoxy-, 1-(4-methylbenzenesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 98-59-9
p-toluenesulfonyl chloride

: 175021-11-1
(3,3-bis-methoxy-cyclobutyl)methanol

: 175021-12-2
(3,3-dimethoxycyclobutyl)methyl p-toluenesulfonate

Guidance literature:: In pyridine; 1.) room temperature, 1 h, 2.) 5 deg C, 16 h;
DOI:10.1021/jo951865b

Reference yield:

: 23761-23-1
3-oxocyclobutanecarboxylic acid

: 175021-12-2
(3,3-dimethoxycyclobutyl)methyl p-toluenesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / p-TsOH / 8 h / Heating

2: 86 percent / LiAlH₄ / diethyl ether / 2 h / Heating

3: 94 percent / pyridine / 1.) room temperature, 1 h, 2.) 5 deg C, 16 h

With lithium aluminium tetrahydride; toluene-4-sulfonic acid; In pyridine; diethyl ether;
DOI:10.1021/jo951865b

Reference yield:

: 98231-07-3
3,3-dimethoxycyclobutanecarboxylic acid methyl ester

: 175021-12-2
(3,3-dimethoxycyclobutyl)methyl p-toluenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / LiAlH₄ / diethyl ether / 2 h / Heating

2: 94 percent / pyridine / 1.) room temperature, 1 h, 2.) 5 deg C, 16 h

With lithium aluminium tetrahydride; In pyridine; diethyl ether;
DOI:10.1021/jo951865b