3-(Chloromethyl)cyclobutan-1-one

Base Information

Chemical Name:3-(Chloromethyl)cyclobutan-1-one
CAS No.:175021-13-3
Molecular Formula:C5H7ClO
Molecular Weight:118.56
Hs Code.:2914290090
European Community (EC) Number:890-822-3
Nikkaji Number:J721.397B
Mol file:175021-13-3.mol

Synonyms:3-(chloromethyl)cyclobutan-1-one;3-(chloromethyl)cyclobutanone;175021-13-3;Cyclobutanone, 3-(chloromethyl)-;SCHEMBL22939265;MFCD11858225;AKOS006221924;PB28331;AS-50845;CS-0054362;EN300-43872;P11243;A881642

Suppliers and Price of 3-(Chloromethyl)cyclobutan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(Chloromethyl)cyclobutan-1-one
100mg
$ 240.00

Crysdot
3-(Chloromethyl)cyclobutanone 95+%
250mg
$ 266.00

Crysdot
3-(Chloromethyl)cyclobutanone 95+%
1g
$ 664.00

Chemenu
3-(Chloromethyl)cyclobutanone 95%
1g
$ 621.00

American Custom Chemicals Corporation
3-(CHLOROMETHYL)CYCLOBUTANONE 95.00%
5G
$ 4199.81

American Custom Chemicals Corporation
3-(CHLOROMETHYL)CYCLOBUTANONE 95.00%
1G
$ 1443.40

AK Scientific
3-(Chloromethyl)cyclobutan-1-one
250mg
$ 691.00

Total 14 raw suppliers

Chemical Property of 3-(Chloromethyl)cyclobutan-1-one

Chemical Property:

PSA：17.07000
LogP:1.20430
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:118.0185425
Heavy Atom Count:7
Complexity:82.1

Purity/Quality:

99%, ^*data from raw suppliers

3-(Chloromethyl)cyclobutan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC1=O)CCl

Technology Process of 3-(Chloromethyl)cyclobutan-1-one

There total 7 articles about 3-(Chloromethyl)cyclobutan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 463961-42-4
2,2-dichloro-3-(chloromethyl)cyclobutan-1-one

: 175021-13-3
3-(chloromethyl)cyclobutan-1-one

Guidance literature:: With acetic acid; zinc; for 4h; Heating;
DOI:10.1021/jo025897s

Reference yield: 31.0%

: 107-05-1
3-chloroprop-1-ene

: 76-02-8
trifluoroacetyl chloride

: 175021-13-3
3-(chloromethyl)cyclobutan-1-one

Guidance literature:: 3-chloroprop-1-ene; trifluoroacetyl chloride; With trichlorophosphate;

With acetic acid; zinc;
DOI:10.1016/j.tet.2012.11.032

Reference yield:

: 23761-23-1
3-oxocyclobutanecarboxylic acid

: 175021-13-3
3-(chloromethyl)cyclobutan-1-one

Guidance literature:: Multi-step reaction with 5 steps

1: 65 percent / p-TsOH / 8 h / Heating

2: 86 percent / LiAlH₄ / diethyl ether / 2 h / Heating

3: 94 percent / pyridine / 1.) room temperature, 1 h, 2.) 5 deg C, 16 h

4: LiCl / dimethylformamide / 16 h / 70 °C

5: conc. HCl / 3 h

With hydrogenchloride; lithium aluminium tetrahydride; toluene-4-sulfonic acid; lithium chloride; In pyridine; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jo951865b