2-(5,6-Dichloropyridin-3-yl)acetonitrile

Base Information

Chemical Name:2-(5,6-Dichloropyridin-3-yl)acetonitrile
CAS No.:54226-45-8
Molecular Formula:C₇H₄Cl₂N₂
Molecular Weight:187.028
Hs Code.:
European Community (EC) Number:843-997-5
Wikidata:Q107896217

Synonyms:2-(5,6-dichloropyridin-3-yl)acetonitrile;54226-45-8;SCHEMBL1141731;AKOS026730105;EN300-134076

Suppliers and Price of 2-(5,6-Dichloropyridin-3-yl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(5,6-Dichloropyridin-3-yl)acetonitrile

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:185.9751535
Heavy Atom Count:11
Complexity:175

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=NC(=C1Cl)Cl)CC#N

Technology Process of 2-(5,6-Dichloropyridin-3-yl)acetonitrile

There total 1 articles about 2-(5,6-Dichloropyridin-3-yl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54226-45-8
2-(5,6-dichloropyridin-3-yl)acetonitrile

: 54127-31-0
5-chloromethyl-2,3-dichloropyridine

Guidance literature:

Reference yield:

: 54226-45-8
2-(5,6-dichloropyridin-3-yl)acetonitrile

: 1073616-66-6
3-chloro-5-(cyanomethyl)-N-[4-(trifluoromethyl)phenyl]-3',6'-dihydro-(2,4'-bipyridine)-1'(2'H)-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / 1,2-dimethoxyethane; ethanol; water / 90 °C / Inert atmosphere

2: hydrogenchloride / dichloromethane; diethyl ether / 45 °C / Inert atmosphere

3: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

With hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; N-ethyl-N,N-diisopropylamine; In 1,2-dimethoxyethane; diethyl ether; ethanol; dichloromethane; water;
DOI:10.1021/jm500818a

Reference yield:

: 64-17-5
ethanol

: 54226-45-8
2-(5,6-dichloropyridin-3-yl)acetonitrile

: C₉H₉Cl₂NO₂

Guidance literature:: ethanol; With acetyl chloride; In chloroform; at 0 ℃; for 0.25h;

2-(5,6-dichloropyridin-3-yl)acetonitrile; In chloroform; at 0 - 22 ℃;