3,4-Diethyl-1H-pyrrole-2-carbaldehyde

Base Information

• Chemical Name: 3,4-Diethyl-1H-pyrrole-2-carbaldehyde
• CAS No.: 1006-26-4
• Molecular Formula: C9H13NO
• Molecular Weight: 151.20600
• Mol file: 1006-26-4.mol

Synonyms:3,4-diethylpyrrole;1H-Pyrrole-2-carboxaldehyde,3,4-diethyl;3,4-diethyl-2-formylpyrrole;3,4-diethyl-pyrrole-2-carboxaldehyde;3,4-diethylpyrrole-2-carboxyaldehyde;3,4-diethylpyrrole-2-carbaldehyde;2-formyl-3,4-diethylpyrrole;

Chemical Property of 3,4-Diethyl-1H-pyrrole-2-carbaldehyde

Chemical Property:

• Melting Point: 42-45℃
• Boiling Point: 244℃
• Flash Point: 107℃
• PSA: 32.86000
• Density: 1.042
• LogP: 1.95200

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-Diethyl-1H-pyrrole-2-carbaldehyde

There total 9 articles about 3,4-Diethyl-1H-pyrrole-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3,4-diethyl-1H-pyrrole (16200-52-5) + sodium acetate (127-09-3) → 3,4-diethylpyrrole-2-carbaldehyde (1006-26-4)

Guidance literature:

3,4-diethyl-1H-pyrrole; With trichlorophosphate; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; for 2h; Inert atmosphere; Reflux;

sodium acetate; In water; for 2h; Reflux;

DOI:10.1002/chem.201501299

Reference yield: 82.0%

3,4-diethyl-1H-pyrrole (16200-52-5) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3,4-diethylpyrrole-2-carbaldehyde (1006-26-4)

Guidance literature:

N,N-dimethyl-formamide; With trichlorophosphate; at 0 ℃; Inert atmosphere;

3,4-diethyl-1H-pyrrole; In dichloromethane; at 20 ℃; for 10h; Inert atmosphere;

With sodium hydroxide; In water; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2013.07.067

Reference yield:

3,4-diethyl-1H-pyrrole (16200-52-5) → 3,4-diethylpyrrole-2-carbaldehyde (1006-26-4)

Guidance literature:

3,4-diethyl-1H-pyrrole; With trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 18.5h; Inert atmosphere;

With potassium hydroxide; In water; at 20 ℃; for 2.5h; Inert atmosphere;

DOI:10.1021/ja907428e

upstream raw materials:

3,4-diethyl-1H-pyrrole

N,N-dimethyl-formamide

4-Nitrohexan-3-ol

4-acetoxy-3-nitrohexane

Downstream raw materials:

1,1'-(1,3-propanediyl)bis(3,4-diethylpyrrole-2-carbaldehyde)

2,3,7,8,12,13,17,18-octaethyl-porphyrin