Carbamic acid phenyl-thiophen-2-yl-methyl ester

Base Information

• Chemical Name: Carbamic acid phenyl-thiophen-2-yl-methyl ester
• CAS No.: 105748-51-4
• Molecular Formula: C₁₂H₁₁NO₂S
• Molecular Weight: 233.291
• Mol file: 105748-51-4.mol

Synonyms:

Chemical Property of Carbamic acid phenyl-thiophen-2-yl-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid phenyl-thiophen-2-yl-methyl ester

There total 3 articles about Carbamic acid phenyl-thiophen-2-yl-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiophene-2-carbaldehyde (98-03-3) → Carbamic acid phenyl-thiophen-2-yl-methyl ester (105748-51-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / magnesium / tetrahydrofuran / 2 h / Ambient temperature

2: 1.) pyridine 2.) liquide ammonia / 1.) benzene, toluene, 0.5 h, 70 deg C

With pyridine; ammonia; magnesium; In tetrahydrofuran;

Reference yield:

bromobenzene (108-86-1,52753-63-6) → Carbamic acid phenyl-thiophen-2-yl-methyl ester (105748-51-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / magnesium / tetrahydrofuran / 2 h / Ambient temperature

2: 1.) pyridine 2.) liquide ammonia / 1.) benzene, toluene, 0.5 h, 70 deg C

With pyridine; ammonia; magnesium; In tetrahydrofuran;

Reference yield:

phosgene (75-44-5) + phenyl-thiophen-2-yl-methanol (26059-21-2,105748-50-3,118759-49-2) → Carbamic acid phenyl-thiophen-2-yl-methyl ester (105748-51-4)

Guidance literature:

With pyridine; ammonia; Multistep reaction; 1.) benzene, toluene, 0.5 h, 70 deg C;

upstream raw materials:

phosgene

phenyl-thiophen-2-yl-methanol

thiophene-2-carbaldehyde

bromobenzene

Downstream raw materials:

(2-Hydroxy-1,2-diphenyl-ethyl)-carbamic acid phenyl-thiophen-2-yl-methyl ester