2-Phenyl-1,3,2-dioxaphospholane

Base Information

• Chemical Name: 2-Phenyl-1,3,2-dioxaphospholane
• CAS No.: 1006-83-3
• Molecular Formula: C8H9O2P
• Molecular Weight: 168.132
• DSSTox Substance ID: DTXSID60453770
• Nikkaji Number: J801.661E
• Wikidata: Q82275001
• Mol file: 1006-83-3.mol

Synonyms:2-phenyl-1,3,2-dioxaphospholane;1006-83-3;1,3,2-Dioxaphospholane, 2-phenyl-;SCHEMBL6669567;DTXSID60453770

Chemical Property of 2-Phenyl-1,3,2-dioxaphospholane

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 168.03401652
• Heavy Atom Count: 11
• Complexity: 117

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COP(O1)C2=CC=CC=C2

Technology Process of 2-Phenyl-1,3,2-dioxaphospholane

There total 6 articles about 2-Phenyl-1,3,2-dioxaphospholane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethylene glycol (107-21-1) + Dichlorophenylphosphine (644-97-3) → 2-phenyl-[1,3,2]dioxaphospholane (1006-83-3)

Guidance literature:

at 5 - 45 ℃; for 3h; Alkaline conditions; Sealed tube;

Reference yield: 55.0%

dimethyl-2,2 germa-2 dioxolane-1,3 (5865-67-8) + Dichlorophenylphosphine (644-97-3) → 2-phenyl-[1,3,2]dioxaphospholane (1006-83-3)

Guidance literature:

In benzene; addition of C6H5PCl2 to Ge dioxolane (benzene, 0°C, N2 or Ar); distillation, concn. of solvent, elem. anal.;

Reference yield:

2-phenylspiro<1,3,2-dioxaphospholane-2,2'-naphtho<1,8-d,e><1,3,2>dithiaphosphorin> (86853-79-4) → 2-phenyl-[1,3,2]dioxaphospholane (1006-83-3) + 1,8-naphthalenedisulfide (209-22-3)

Guidance literature:

In chloroform-d1; Ambient temperature;

DOI:10.1021/jo00169a044

upstream raw materials:

ethylene glycol

Dichlorophenylphosphine

bis(dimethylamino)phenyl phosphine

2-phenylspiro<1,3,2-dioxaphospholane-2,2'-naphtho<1,8-d,e><1,3,2>dithiaphosphorin>

Downstream raw materials:

2,3-benzo-5-phenyl-1,4,6,9-tetraoxa-5-phosphaspiro<4.4>non-2-ene

5-phenyl-1,4,6,9-tetraoxa-5-phosphaspiro<4.4>nonane

7-methyl-5-phenyl-1,4,6-trioxa-5λ⁵-phospha-spiro[4.4]non-7-ene

Phenyl-phosphinsaeure-(β-propionyloxy-ethyl)-ester