(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid
CAS No.:100723-71-5
Molecular Formula:C₁₄H₁₈N₂O₅S
Molecular Weight:326.373
Hs Code.:
DSSTox Substance ID:DTXSID30474553
Wikidata:Q82304634
Mol file:100723-71-5.mol

Synonyms:100723-71-5;(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid;(2S)-1-[2-(4-methylbenzenesulfonamido)acetyl]pyrrolidine-2-carboxylic acid;Tos-Gly-Pro-OH;(2S)-1-[2-[(4-methylphenyl)sulfonylamino]acetyl]pyrrolidine-2-carboxylic acid;L-Proline, N-[(4-methylphenyl)sulfonyl]glycyl-;DTXSID30474553;MFCD00238391;(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicacid;AKOS016010661;NS-05455;CS-0215843;EN300-303024

Suppliers and Price of (S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicAcid
500mg
$ 130.00

Crysdot
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicacid 97%
1g
$ 94.00

Chemenu
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicacid 97%
5g
$ 296.00

American Custom Chemicals Corporation
(S)-1-(2-(4-METHYLPHENYLSULFONAMIDO)ACETYL)PYRROLIDINE-2-CARBOXYLIC ACID 95.00%
1G
$ 798.00

American Custom Chemicals Corporation
(S)-1-(2-(4-METHYLPHENYLSULFONAMIDO)ACETYL)PYRROLIDINE-2-CARBOXYLIC ACID 95.00%
5MG
$ 504.41

Alichem
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicacid
5g
$ 416.00

Alichem
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicacid
25g
$ 1386.00

AK Scientific
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicacid
5g
$ 1011.00

Total 28 raw suppliers

Chemical Property of (S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid

Chemical Property:

PSA：112.16000
LogP:1.75850
Storage Temp.:-15°C
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:326.09364285
Heavy Atom Count:22
Complexity:520

Purity/Quality:

97% ^*data from raw suppliers

(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCCC2C(=O)O
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)O

Technology Process of (S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid

There total 2 articles about (S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1080-44-0
N-Tosylglycine

: 100723-71-5
Tos-Gly-Pro-OH

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether; PCl₅

2: aqueous NaOH; dioxane

With 1,4-dioxane; sodium hydroxide; diethyl ether; phosphorus pentachloride;
DOI:10.1021/ja01569a071

Reference yield:

: 56218-62-3
2-(4-methylphenylsulfonamido)acetyl chloride

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 100723-71-5
Tos-Gly-Pro-OH

Guidance literature:: With 1,4-dioxane; sodium hydroxide;
DOI:10.1021/ja01569a071

Reference yield:

: 100723-71-5
Tos-Gly-Pro-OH

: 109968-82-3,109968-98-1
1-[2-(Toluene-4-sulfonylamino)-acetyl]-pyrrolidine-2-carboxylic acid [2-morpholin-4-yl-2-oxo-1-(4-thiocarbamoyl-benzyl)-ethyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 1) 4-nitrophenole, DCC, 2) TEA / 1) pyridine, 2 h, 0 deg C, 12 h, RT, 2) 4 h, reflux

2: 1) 4-nitrophenole, DCC / 1) pyridine, 2 h, 0 deg C, 12 h, RT, 2) 12 h

3: TEA, H₂S / pyridine / Ambient temperature

With 4-nitro-phenol; TEA; hydrogen sulfide; dicyclohexyl-carbodiimide; In pyridine;