4-(Benzyloxy)pyridine-2-carboxylic acid

Base Information

Chemical Name:4-(Benzyloxy)pyridine-2-carboxylic acid
CAS No.:100727-49-9
Molecular Formula:C13H11NO3
Molecular Weight:229.235
Hs Code.:
European Community (EC) Number:889-851-4
DSSTox Substance ID:DTXSID50605069
Wikidata:Q82503204
Mol file:100727-49-9.mol

Synonyms:100727-49-9;4-(benzyloxy)pyridine-2-carboxylic acid;2-Pyridinecarboxylic acid, 4-(phenylmethoxy)-;4-phenylmethoxypyridine-2-carboxylic acid;4-(Benzyloxy)picolinic acid;2-pyridinecarboxylic acid,4-(phenylmethoxy)-;SCHEMBL11617562;DTXSID50605069;MFCD11181375;AKOS009311352;4-(benzyloxy)pyridine-2-carboxylicacid;BS-44851;DB-166536;CS-0264882;EN300-95095;E89060;Z381411818

Suppliers and Price of 4-(Benzyloxy)pyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(Benzyloxy)pyridine-2-carboxylic acid

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:229.07389321
Heavy Atom Count:17
Complexity:251

Purity/Quality:: HPLC≥98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC(=NC=C2)C(=O)O

Technology Process of 4-(Benzyloxy)pyridine-2-carboxylic acid

There total 6 articles about 4-(Benzyloxy)pyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.5%

: 100382-00-1
4-benzyloxypyridine-2-carbonitrile

: 100727-49-9
4-(benzyloxy)picolinic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; at 90 ℃; for 1h;

Reference yield:

: 5470-22-4
4-chloropicolinic acid

: 100-51-6,185532-71-2
benzyl alcohol

: 100727-49-9
4-(benzyloxy)picolinic acid

Guidance literature:: benzyl alcohol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; for 0.333333h;

4-chloropicolinic acid; at 85 ℃; for 3.5h;

Reference yield:

: 100-51-6,185532-71-2
benzyl alcohol

: 100727-49-9
4-(benzyloxy)picolinic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 - 20 °C

1.2: 100 °C

2.1: N,N-Dimethylcarbamoyl chloride / dichloromethane / 0 - 20 °C

3.1: water; sodium hydroxide / ethanol / 1 h / 90 °C

With water; sodium hydride; sodium hydroxide; N,N-Dimethylcarbamoyl chloride; In ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;