3-Octanone, 1-(4-methylphenyl)-

Base Information

• Chemical Name: 3-Octanone, 1-(4-methylphenyl)-
• CAS No.: 100765-50-2
• Molecular Formula: C15H22O
• Molecular Weight: 218.339
• Mol file: 100765-50-2.mol

Synonyms:

Chemical Property of 3-Octanone, 1-(4-methylphenyl)-

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Octanone, 1-(4-methylphenyl)-

There total 7 articles about 3-Octanone, 1-(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-octen-3-ol (3391-86-4) + sodium 4-methylbenzenesulfinate (824-79-3) → 1-(4-methylphenyl)octan-3-one (100765-50-2)

Guidance literature:

With 4,7-Dimethyl-1,10-phenanthroline; palladium(II) trifluoroacetate; copper (II) trifluoroacetate hydrate; In 1,4-dioxane; at 100 ℃; for 20h; regioselective reaction; Sealed tube;

DOI:10.1021/acs.joc.5b01463

Reference yield: 81.0%

1-octen-3-ol (3391-86-4) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 1-(4-methylphenyl)octan-3-one (100765-50-2)

Guidance literature:

With tetrabutylammomium bromide; oxygen; palladium diacetate; In water; dimethyl sulfoxide; N,N-dimethyl-formamide; at 120 ℃; under 760.051 Torr; Schlenk technique;

DOI:10.1002/chem.201302962

Reference yield: 75.0%

butyl magnesium bromide (693-04-9) + 4-Methylbenzyl chloride (104-82-5) + N-(1-Phenylethyl)-2-methyleneaziridine → 1-(4-methylphenyl)octan-3-one (100765-50-2)

Guidance literature:

butyl magnesium bromide; N-(1-Phenylethyl)-2-methyleneaziridine; With copper(l) iodide; In tetrahydrofuran; at -30 - 20 ℃; for 24h;

4-Methylbenzyl chloride; In tetrahydrofuran; at 20 - 40 ℃;

With acetic acid; In hexane; at 20 ℃; Further stages.;

DOI:10.1039/b005623p

upstream raw materials:

butyl magnesium bromide

4-Methylbenzyl chloride

1-octen-3-ol

para-bromotoluene