ETHYL (2E)-4-HYDROXY-BUT-2-ENOATE

Base Information

Chemical Name:ETHYL (2E)-4-HYDROXY-BUT-2-ENOATE
CAS No.:10080-68-9
Molecular Formula:C6H10O3
Molecular Weight:130.144
Hs Code.:2918199090
Mol file:10080-68-9.mol

Synonyms:(E)-4-Hydroxycrotonoic Acid Ethyl Ester;

Suppliers and Price of ETHYL (2E)-4-HYDROXY-BUT-2-ENOATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(E)-4-HydroxycrotonoicAcidEthylEster(~85%)
2.5g
$ 1135.00

Medical Isotopes, Inc.
(E)-4-HydroxycrotonoicAcidEthylEster
250 mg
$ 650.00

Matrix Scientific
Ethyl4-hydroxycrotonate
1g
$ 900.00

Matrix Scientific
Ethyl4-hydroxycrotonate
5g
$ 1980.00

American Custom Chemicals Corporation
ETHYL (2E)-4-HYDROXY-BUT-2-ENOATE 95.00%
5MG
$ 504.32

A1 Biochem Labs
Ethyl4-hydroxycrotonate 95%
1 g
$ 550.00

Total 6 raw suppliers

Chemical Property of ETHYL (2E)-4-HYDROXY-BUT-2-ENOATE

Chemical Property:

Boiling Point:119-120 °C(Press: 13 Torr)
PKA:13.29±0.10(Predicted)
PSA：46.53000
Density:1.077 g/cm3
LogP:0.09800
Storage Temp.:Refrigerator
Solubility.:DCM, Ethyl Acetate

Purity/Quality:

98%,99%, ^*data from raw suppliers

(E)-4-HydroxycrotonoicAcidEthylEster(~85%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (E)-4-Hydroxycrotonoic Acid Ethyl Ester is an intermediate in the preparation of unusual amino acids that are potential Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors.

Technology Process of ETHYL (2E)-4-HYDROXY-BUT-2-ENOATE

There total 25 articles about ETHYL (2E)-4-HYDROXY-BUT-2-ENOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 32223-97-5
(+/-)-ethyl-3,4-epoxybutanoate

: 10080-68-9
(E)-ethyl 4-hydroxybut-2-enoate

Guidance literature:: With base; In tetrahydrofuran; Ambient temperature;
DOI:10.1039/c39860000836

Reference yield: 88.0%

: 26367-48-6
fumaric acid ethyl ester mono chloride

: 10080-68-9
(E)-ethyl 4-hydroxybut-2-enoate

Guidance literature:: With zinc(II) tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; In diethyl ether; at 0 ℃; for 0.5h;
DOI:10.1246/bcsj.61.2684