5-Methyl-3(2H)-pyridazinone

Base Information

• Chemical Name: 5-Methyl-3(2H)-pyridazinone
• CAS No.: 54709-94-3
• Molecular Formula: C5H6 N2 O
• Molecular Weight: 110.11
• Hs Code.: 2933990090
• Mol file: 54709-94-3.mol

Synonyms:3-Pyridazinol,5-methyl- (6CI);3-Methyl-5,6-diaza-2,4-cyclohexadien-1-one;5-Methyl-3(2H)-pyridazinone;5-Methylpyridazin-3-one;NSC 300284;

Chemical Property of 5-Methyl-3(2H)-pyridazinone

Chemical Property:

• Melting Point: 151-153 °C
• Refractive Index: 1.576
• PKA: 11.50±0.40(Predicted)
• PSA: 45.75000
• Density: 1.22g/cm3
• LogP: 0.07830
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

5-Methyl-3(2H)-pyridazinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Methyl-3(2H)-pyridazinone

There total 13 articles about 5-Methyl-3(2H)-pyridazinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-hydroxy-4-methyl-5H-furan-2-one (40834-42-2) → 5-methylpyridazin-3(2H)-one (54709-94-3)

Guidance literature:

With hydrazine; In tetrahydrofuran; at 20 - 60 ℃;

Reference yield: 73.0%

5-(1,2-diaza-1-t-butyl-4-methylbutadien-4-ylidene)-2,2-dimethyl-1,3-dioxan-4,6-dione (83297-15-8) → 5-methylpyridazin-3(2H)-one (54709-94-3)

Guidance literature:

at 750 ℃; for 2h; under 0.01 - 0.1 Torr;

Reference yield: 70.0%

N'-acryloyl-4-methyl-N-(2-methylallyl)benzenesulfonohydrazide (1173165-21-3) → 5-methylpyridazin-3(2H)-one (54709-94-3)

Guidance literature:

With 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(iso-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methylene ruthenium(II) dichloride; In dichloromethane; at 70 ℃; for 72h; Sealed tube; Inert atmosphere;

DOI:10.1039/b904363b

upstream raw materials:

6-chloro-5-methyl-2H-pyridazin-3-one

5-methyl-3-oxo-2,3-dihydro-pyridazine-4-carboxylic acid

2-ethoxy-3-methyl-2H-furan-5-one

5-(1,2-diaza-1-t-butyl-4-methylbutadien-4-ylidene)-2,2-dimethyl-1,3-dioxan-4,6-dione

Downstream raw materials:

4-methylpyridazine

3-chloro-5-methylpyridazine