6-propoxy-2-naphthaldehyde

Base Information

• Chemical Name: 6-propoxy-2-naphthaldehyde
• CAS No.: 100234-29-5
• Molecular Formula: C₁₄H₁₄O₂
• Molecular Weight: 214.264
• Mol file: 100234-29-5.mol

Synonyms:

Chemical Property of 6-propoxy-2-naphthaldehyde

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

6-Propoxy-2-naphthaldehyde 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-propoxy-2-naphthaldehyde

There total 2 articles about 6-propoxy-2-naphthaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

6-hydroxynaphthalene-2-carbaldehyde (78119-82-1) + 1-iodo-propane (107-08-4) → 6-propoxy-2-naphthaldehyde (100234-29-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 4h; Inert atmosphere;

DOI:10.1021/acs.joc.9b02603

Reference yield: 25.0%

2-propyloxy-6-bromonaphthalene (97476-14-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 6-propoxy-2-naphthaldehyde (100234-29-5)

Guidance literature:

2-propyloxy-6-bromonaphthalene; With iodine; magnesium; In tetrahydrofuran; for 4h; Reflux; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

With water; acetic acid; In tetrahydrofuran;

DOI:10.1016/j.bmc.2009.01.074

Reference yield:

6-propoxy-2-naphthaldehyde (100234-29-5) + N-tosyl-3-butenylamine (10285-80-0) → trans-4-chloro-2-(6-propoxynaphthalen-2-yl)-1-tosylpiperidine + cis-4-chloro-2-(6-propoxynaphthalen-2-yl)-1-tosylpiperidine

Guidance literature:

With titanium tetrachloride; toluene-4-sulfonic acid; In dichloromethane; at 60 ℃; for 168h; Overall yield = 37 percent; Overall yield = 703 mg; Inert atmosphere;

DOI:10.1021/acs.joc.9b02603

upstream raw materials:

2-propyloxy-6-bromonaphthalene

N,N-dimethyl-formamide

6-hydroxynaphthalene-2-carbaldehyde

1-iodo-propane