1-<4-(2-carboxyethyl)phenoxy>-3-1-(N⁴-phenyl-piperazinyl)>propane

Base Information

• Chemical Name: 1-<4-(2-carboxyethyl)phenoxy>-3-1-(N⁴-phenyl-piperazinyl)>propane
• CAS No.: 134858-58-5
• Molecular Formula: C₂₃H₂₈N₂O₄
• Molecular Weight: 396.486
• Mol file: 134858-58-5.mol

Synonyms:

Chemical Property of 1-<4-(2-carboxyethyl)phenoxy>-3-1-(N⁴-phenyl-piperazinyl)>propane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-<4-(2-carboxyethyl)phenoxy>-3-1-(N⁴-phenyl-piperazinyl)>propane

There total 1 articles about 1-<4-(2-carboxyethyl)phenoxy>-3-1-(N⁴-phenyl-piperazinyl)>propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

3-(4-hydroxybenzoyl)propionic acid (56872-39-0) → 1-<4-(2-carboxyethyl)phenoxy>-3-1-(N4-phenyl-piperazinyl)>propane (134858-58-5)

Guidance literature:

With sodium hydroxide; In ethanol; for 8h; Heating;

Reference yield: 56.0%

N1-(4-chlorobenzoyl)-4-methoxyphenylhydrazine (16390-07-1) + 1-<4-(2-carboxyethyl)phenoxy>-3-1-(N4-phenyl-piperazinyl)>propane (134858-58-5) → (1-(4-Chloro-benzoyl)-5-methoxy-2-{4-[3-(4-phenyl-piperazin-1-yl)-propoxy]-phenyl}-1H-indol-3-yl)-acetic acid; hydrochloride (134858-68-7)

Guidance literature:

With hydrogenchloride; acetic acid; at 80 ℃; for 6h;

upstream raw materials:

3-(4-hydroxybenzoyl)propionic acid

Downstream raw materials:

(1-(4-Chloro-benzoyl)-5-methoxy-2-{4-[3-(4-phenyl-piperazin-1-yl)-propoxy]-phenyl}-1H-indol-3-yl)-acetic acid; hydrochloride