Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate

Base Information

Chemical Name:Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate
CAS No.:101466-85-7
Molecular Formula:C12H11F3O2
Molecular Weight:244.213
Hs Code.:
DSSTox Substance ID:DTXSID70705772
Mol file:101466-85-7.mol

Synonyms:Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate;Ethyl 4-trifluoromethylcinnamate;DTXSID70705772;4-trifluoromethylcinnamic acid ethyl ester

Suppliers and Price of Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:244.07111408
Heavy Atom Count:17
Complexity:276

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=CC1=CC=C(C=C1)C(F)(F)F

Technology Process of Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate

There total 35 articles about Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 101466-85-7,128408-03-7
ethyl (E)-4-trifluoromethylcinnamate

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

4-Trifluoromethylbenzaldehyde; In tetrahydrofuran; at 0 - 25 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.bmc.2021.116299

Reference yield: 98.0%

: 64-17-5
ethanol

: 2062-26-2,87212-84-8,16642-92-5
3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid

: 101466-85-7,128408-03-7
ethyl (E)-4-trifluoromethylcinnamate

Guidance literature:: With sulfuric acid; In water; at 82 ℃; for 22h; Reagent/catalyst;
DOI:10.1016/j.tet.2020.131873

Reference yield: 98.0%

: 98-56-6
4-chlorobenzotrifluoride

: 140-88-5,9003-32-1
ethyl acrylate

: 101466-85-7
ethyl 4-trifluoromethylcinnamate

Guidance literature:: With potassium carbonate; In ethanol; water; N,N-dimethyl-formamide; at 100 ℃; for 4h; Green chemistry;
DOI:10.1016/j.apcata.2014.02.002