4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid

Base Information

Chemical Name:4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid
CAS No.:288249-83-2
Molecular Formula:C₁₉H₂₂N₄O₄
Molecular Weight:370.408
Hs Code.:

Synonyms:

Suppliers and Price of 4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid

There total 8 articles about 4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 288249-82-1
ethyl 4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetate

: 288249-83-2
4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid

Guidance literature:: With sodium hydroxide; In ethanol; water; for 0.5h; Heating / reflux;

Reference yield:

: 16588-15-1
2-chloro-5-nitro-benzamide

: 288249-83-2
4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid

Guidance literature:: Multi-step reaction with 6 steps

1: benzenesulfonyl chloride / DMF (N,N-dimethyl-formamide); toluene / 3 h / 20 - 145 °C

2: sodium hydride / DMF (N,N-dimethyl-formamide) / 1 h / Ice cooling

3: iron; ammonium chloride / ethanol; water / 0.83 h / 65 °C / Heating / reflux

4: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / DMF (N,N-dimethyl-formamide) / 5 h / 20 °C

5: potassium carbonate; potassium iodide / DMF (N,N-dimethyl-formamide); toluene / 4 h / 60 °C

6: sodium hydroxide / ethanol; water / 0.5 h / Heating / reflux

With sodium hydroxide; iron; sodium hydride; potassium carbonate; ammonium chloride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; benzenesulfonyl chloride; potassium iodide; In DMF (N,N-dimethyl-formamide); ethanol; water; toluene;

Reference yield:

: 206885-36-1
5-amino-2-neopentyloxybenzonitrile

: 288249-83-2
4-[N-(3-cyano-4-neopentyloxyphenyl)carbamoyl]-3-methylpyrazol-1-ylacetatic acid

Guidance literature:: Multi-step reaction with 3 steps

1: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / DMF (N,N-dimethyl-formamide) / 5 h / 20 °C

2: potassium carbonate; potassium iodide / DMF (N,N-dimethyl-formamide); toluene / 4 h / 60 °C

3: sodium hydroxide / ethanol; water / 0.5 h / Heating / reflux

With sodium hydroxide; potassium carbonate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; potassium iodide; In DMF (N,N-dimethyl-formamide); ethanol; water; toluene;