3-methoxy-2-phenyl-3-methylindolenine

Base Information

• Chemical Name: 3-methoxy-2-phenyl-3-methylindolenine
• CAS No.: 78024-78-9
• Molecular Formula: C₁₆H₁₅NO
• Molecular Weight: 237.301
• Mol file: 78024-78-9.mol

Synonyms:

Chemical Property of 3-methoxy-2-phenyl-3-methylindolenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methoxy-2-phenyl-3-methylindolenine

There total 3 articles about 3-methoxy-2-phenyl-3-methylindolenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 3-Chlor-3-methyl-2-phenyl-indolenin (65837-35-6) → 3-methoxy-2-phenyl-3-methylindolenine (78024-78-9)

Guidance literature:

With sodium methylate; for 2h;

DOI:10.1021/jo00146a015

Reference yield: 82.0%

methanol (67-56-1) + 2-phenyl-3-methyl-1H-indole (10257-92-8) → 3-methoxy-2-phenyl-3-methylindolenine (78024-78-9)

Guidance literature:

With 1-Chloro-1H-indole-2,3-dione; for 3h; Ambient temperature;

DOI:10.1021/jo00146a015

Reference yield:

2-phenyl-3-methyl-1H-indole (10257-92-8) → 3-methoxy-2-phenyl-3-methylindolenine (78024-78-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 4.79 mmol / Br₂, triethylamine / CH₂Cl₂ / 0.17 h / Ambient temperature

2: 3.08 mmol / CH₂Cl₂ / 0.67 h / Ambient temperature

With bromine; triethylamine; In dichloromethane;

upstream raw materials:

methanol

3-Chlor-3-methyl-2-phenyl-indolenin

2-phenyl-3-methyl-1H-indole

Downstream raw materials:

5-Chloro-1,1'-dimethyl-2,2'-diphenyl-1,2-dihydro-1'H-[2,3']biindolyl-3-one