(-)-2-cyano-6-L-menthylpyridine

Base Information

Chemical Name:(-)-2-cyano-6-L-menthylpyridine
CAS No.:204917-69-1
Molecular Formula:C₁₆H₂₂N₂
Molecular Weight:242.364
Hs Code.:

Synonyms:

Suppliers and Price of (-)-2-cyano-6-L-menthylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-2-cyano-6-L-menthylpyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-2-cyano-6-L-menthylpyridine

There total 4 articles about (-)-2-cyano-6-L-menthylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 7677-24-9
trimethylsilyl cyanide

: 204917-67-9
(-)-2-L-menthylpyridine-N-oxide

: 204917-69-1
(-)-2-cyano-6-L-menthylpyridine

Guidance literature:: With N,N-Dimethylcarbamoyl chloride; In dichloromethane; for 72h;
DOI:10.1016/S0957-4166(97)00619-8

Reference yield:

: 109-04-6
2-bromo-pyridine

: 204917-69-1
(-)-2-cyano-6-L-menthylpyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Mg, 1,2-dibromoethane, 2.) Pd(dppf)Cl₂ / 1.) THF, 50 deg C, 16 h, 2.) THF, 0 deg C, 48 h

2: 89 percent / m-cpba / CH₂Cl₂ / 72 h / Ambient temperature

3: 78 percent / dimethylcarbamoyl chloride / CH₂Cl₂ / 72 h

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; magnesium; ethylene dibromide; 3-chloro-benzenecarboperoxoic acid; N,N-Dimethylcarbamoyl chloride; In dichloromethane;
DOI:10.1016/S0957-4166(97)00619-8

Reference yield:

: 16052-42-9
(1R,2S,5R)-menthyl chloride

: 204917-69-1
(-)-2-cyano-6-L-menthylpyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Mg, 1,2-dibromoethane, 2.) Pd(dppf)Cl₂ / 1.) THF, 50 deg C, 16 h, 2.) THF, 0 deg C, 48 h

2: 89 percent / m-cpba / CH₂Cl₂ / 72 h / Ambient temperature

3: 78 percent / dimethylcarbamoyl chloride / CH₂Cl₂ / 72 h

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; magnesium; ethylene dibromide; 3-chloro-benzenecarboperoxoic acid; N,N-Dimethylcarbamoyl chloride; In dichloromethane;
DOI:10.1016/S0957-4166(97)00619-8