1-(1-{4-[(3R,5S)-5-(diphenyltrimethylsilyloxymethyl)pyrrolidin-3-yloxymethyl]phenyl}ethoxy)-2,2,6,6-tetramethylpiperidine

Base Information

• Chemical Name: 1-(1-{4-[(3R,5S)-5-(diphenyltrimethylsilyloxymethyl)pyrrolidin-3-yloxymethyl]phenyl}ethoxy)-2,2,6,6-tetramethylpiperidine
• CAS No.: 1061611-21-9
• Molecular Formula: C₃₈H₅₄N₂O₃Si
• Molecular Weight: 614.944
• Mol file: 1061611-21-9.mol

Synonyms:

Chemical Property of 1-(1-{4-[(3R,5S)-5-(diphenyltrimethylsilyloxymethyl)pyrrolidin-3-yloxymethyl]phenyl}ethoxy)-2,2,6,6-tetramethylpiperidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1-{4-[(3R,5S)-5-(diphenyltrimethylsilyloxymethyl)pyrrolidin-3-yloxymethyl]phenyl}ethoxy)-2,2,6,6-tetramethylpiperidine

There total 1 articles about 1-(1-{4-[(3R,5S)-5-(diphenyltrimethylsilyloxymethyl)pyrrolidin-3-yloxymethyl]phenyl}ethoxy)-2,2,6,6-tetramethylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

diphenyl-((2S,4R)-4-{4-[1-(2,2,6,6-tetramethylpiperidin-1-yl-oxy)ethyl]benzyloxy}pyrrolidin-2-yl)methanol (1061611-27-5) + 1-(Trimethylsilyl)imidazole (18156-74-6) → 1-(1-{4-[(3R,5S)-5-(diphenyltrimethylsilyloxymethyl)pyrrolidin-3-yloxymethyl]phenyl}ethoxy)-2,2,6,6-tetramethylpiperidine (1061611-21-9)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1055/s-2008-1067146

upstream raw materials:

diphenyl-((2S,4R)-4-{4-[1-(2,2,6,6-tetramethylpiperidin-1-yl-oxy)ethyl]benzyloxy}pyrrolidin-2-yl)methanol

1-(Trimethylsilyl)imidazole