methyl glycyrrhetinate

Base Information

• Chemical Name: methyl glycyrrhetinate
• CAS No.: 10379-74-5
• Molecular Formula: C₃₁H₄₈O₄
• Molecular Weight: 484.72
• Mol file: 10379-74-5.mol

Synonyms:

Chemical Property of methyl glycyrrhetinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl glycyrrhetinate

There total 52 articles about methyl glycyrrhetinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

enoxolone (471-53-4) + methyl iodide (74-88-4) → methyl glycyrrhetinate (1477-44-7,5092-01-3,7558-31-8,10379-74-5,10379-79-0,21857-94-3,118492-16-3)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 24h;

DOI:10.1002/ardp.200900051

Reference yield: 99.54%

enoxolone (471-53-4) + diazomethyl-trimethyl-silane (18107-18-1) → methyl glycyrrhetinate (1477-44-7,5092-01-3,7558-31-8,10379-74-5,10379-79-0,21857-94-3,118492-16-3)

Guidance literature:

In methanol; diethyl ether; at 0 - 20 ℃; for 2h;

DOI:10.1002/anie.201910051

Reference yield: 99.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + enoxolone (471-53-4) → methyl glycyrrhetinate (1477-44-7,5092-01-3,7558-31-8,10379-74-5,10379-79-0,21857-94-3,118492-16-3)

Guidance literature:

In methanol; diethyl ether; at 0 ℃;

DOI:10.1016/j.tet.2008.10.035

upstream raw materials:

enoxolone

18β-glycyrrhetinic acid

methyl iodide

glycyrrhetinic acid 30-methylester

Downstream raw materials:

methyl (3β)-3-([(4-methylphenyl)sulfonyl]oxy)-11-oxo-olean-12-en-30-oate

C₆₀H₇₈O₁₀

C₆₀H₇₈O₁₀

C₆₀H₇₆O₁₁