(S)-tert-Butyl (1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate

Base Information

Chemical Name:(S)-tert-Butyl (1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate
CAS No.:102507-25-5
Molecular Formula:C17H24N2O4
Molecular Weight:320.389
Hs Code.:
DSSTox Substance ID:DTXSID701127593
Mol file:102507-25-5.mol

Synonyms:102507-25-5;(S)-tert-Butyl (1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate;tert-butyl N-[(3S)-1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl]carbamate;tert-butyl N-[(3S)-2,2-dimethyl-4-oxo-1-phenylmethoxyazetidin-3-yl]carbamate;Carbamic acid, N-[(3S)-2,2-dimethyl-4-oxo-1-(phenylmethoxy)-3-azetidinyl]-, 1,1-dimethylethyl ester;SCHEMBL9825210;MEKOFWOLQDJVOL-CYBMUJFWSA-N;DTXSID701127593;CEA50725;AKOS030628163;SS-5133;CS-0039560;W12437;(S)-tert-butyl 1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-ylcarbamate;tert-Butyl (S)-(1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate;(3S)-3-[(t-butyloxycarbonyl)amino]-4,4-dimethyl-1-(phenylmethoxy)-2-azetidinone;1,1-Dimethylethyl N-[(3S)-2,2-dimethyl-4-oxo-1-(phenylmethoxy)-3-azetidinyl]carbamate

Suppliers and Price of (S)-tert-Butyl (1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (S)-tert-Butyl (1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:320.17360725
Heavy Atom Count:23
Complexity:450

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(C(=O)N1OCC2=CC=CC=C2)NC(=O)OC(C)(C)C)C
Isomeric SMILES:CC1([C@@H](C(=O)N1OCC2=CC=CC=C2)NC(=O)OC(C)(C)C)C

Technology Process of (S)-tert-Butyl (1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate

There total 14 articles about (S)-tert-Butyl (1-(benzyloxy)-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 102507-19-7
(S)-tert-butyl 1-(benzyloxyamino)-3-hydroxy-3-methyl-1-oxobutan-2-ylcarbamate

: 102507-25-5
(3S)-3-[(t-Butyloxycarbonyl)amino]-4,4-dimethyl-1-(phenylmethoxy)-2-azetidinone

Guidance literature:: (S)-tert-butyl 1-(benzyloxyamino)-3-hydroxy-3-methyl-1-oxobutan-2-ylcarbamate; With sulfur trioxide pyridine complex; In pyridine; at 0 ℃; for 2h;

With potassium carbonate; In water; ethyl acetate; for 2h; Reflux;

Reference yield: 58.0%

: 107982-90-1
((S)-1-Benzyloxycarbamoyl-2-methyl-2-sulfooxy-propyl)-carbamic acid tert-butyl ester; compound with 2-methyl-pyridine

: 102507-25-5
(3S)-3-[(t-Butyloxycarbonyl)amino]-4,4-dimethyl-1-(phenylmethoxy)-2-azetidinone

: 106334-44-5
(1-Benzyloxy-3,3-dimethyl-4-oxo-azetidin-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: With potassium hydroxide; potassium tetraborate; In water; at 70 ℃; for 0.75h; Yields of byproduct given;
DOI:10.1016/S0040-4039(00)84643-2

Reference yield: 50.0%

: 107982-89-8
((S)-1-Benzyloxycarbamoyl-2-methyl-2-sulfooxy-propyl)-carbamic acid tert-butyl ester; compound with pyridine

: 102507-25-5
(3S)-3-[(t-Butyloxycarbonyl)amino]-4,4-dimethyl-1-(phenylmethoxy)-2-azetidinone

: 106334-44-5
(1-Benzyloxy-3,3-dimethyl-4-oxo-azetidin-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: With potassium carbonate; In water; ethyl acetate; for 2h; Yields of byproduct given; Heating;
DOI:10.1016/S0040-4039(00)84643-2