C₅₆H₇₉N₇O₁₃

Base Information

• Chemical Name: C₅₆H₇₉N₇O₁₃
• CAS No.: 1305317-57-0
• Molecular Formula: C₅₆H₇₉N₇O₁₃
• Molecular Weight: 1058.28
• Mol file: 1305317-57-0.mol

Synonyms:

Chemical Property of C₅₆H₇₉N₇O₁₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₆H₇₉N₇O₁₃

There total 11 articles about C₅₆H₇₉N₇O₁₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

C24H28N4O8 (1305317-53-6) + C32H53N3O6 (1305317-54-7) → C56H79N7O13 (1305317-57-0)

Guidance literature:

With sodium hydrogencarbonate; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/np200163g

Reference yield:

(S)-2-(tert-butoxycarbonylamino)-3-(4-hydroxy-3-iodo-5-nitrophenyl)propanoic acid (1253795-07-1) → C56H79N7O13 (1305317-57-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: potassium carbonate / acetone / 48 h / Reflux

2.1: trifluoroacetic acid / dichloromethane

3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide; acetonitrile

3.3: 80 °C / Inert atmosphere

4.1: trifluoroacetic acid / dichloromethane

5.1: sodium hydrogencarbonate; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one / tetrahydrofuran / 0 - 20 °C

With sodium hydrogencarbonate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetone; acetonitrile; 3.3: Suzuki-Miyaura coupling;

DOI:10.1021/np200163g

Reference yield:

(S)-methyl 2-(tert-butoxycarbonylamino)-3-(3-iodo-4-methoxy-5-nitrophenyl)propanoate (1253795-12-8) → C56H79N7O13 (1305317-57-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: trifluoroacetic acid / dichloromethane

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide; acetonitrile

2.3: 80 °C / Inert atmosphere

3.1: trifluoroacetic acid / dichloromethane

4.1: sodium hydrogencarbonate; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one / tetrahydrofuran / 0 - 20 °C

With sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile; 2.3: Suzuki-Miyaura coupling;

DOI:10.1021/np200163g

upstream raw materials:

(S)-2-(tert-butoxycarbonyl(methyl)amino)-2-(4-hydroxy-3-iodophenyl)acetic acid

C₂₉H₃₆N₄O₁₀

C₂₄H₂₈N₄O₈

C₃₂H₅₃N₃O₆