3,5-Diphenylpyridazine

Base Information

• Chemical Name: 3,5-Diphenylpyridazine
• CAS No.: 1026-46-6
• Molecular Formula: C16H12N2
• Molecular Weight: 232.285
• DSSTox Substance ID: DTXSID60440029
• Nikkaji Number: J959.558I
• Wikidata: Q82256180
• ChEMBL ID: CHEMBL194198
• Mol file: 1026-46-6.mol

Synonyms:3,5-diphenylpyridazine;3,5-Diphenyl-pyridazine;CHEMBL194198;1026-46-6;3,5-diphenylpyri-dazine;SCHEMBL221868;DTXSID60440029;RTNPJCQBMCRDSE-UHFFFAOYSA-N;BDBM50173693

Chemical Property of 3,5-Diphenylpyridazine

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 232.100048391
• Heavy Atom Count: 18
• Complexity: 242

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC(=NN=C2)C3=CC=CC=C3

Technology Process of 3,5-Diphenylpyridazine

There total 23 articles about 3,5-Diphenylpyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C23H20N2O2S → 3,5-Diphenylpyridazine (1026-46-6)

Guidance literature:

With sodium hydroxide; In acetonitrile; at 80 ℃;

Reference yield: 83.0%

3-phenyl-[1,2,4,5]tetrazine (36022-11-4) + phenylacetylene (536-74-3) → 3,4-diphenylpyridazine (37385-32-3) + 3,5-Diphenylpyridazine (1026-46-6)

Guidance literature:

In 1,4-dioxane; at 70 ℃; for 192h;

DOI:10.1021/ja00057a019

Reference yield: 76.2%

3,5-dichloropyridazine (1837-55-4) + phenylboronic acid (98-80-6) → 3,5-Diphenylpyridazine (1026-46-6) + 5-chloro-3-phenylpyridazine (1426548-41-5) + 3-chloro-5-phenyl-pyridazine (86663-08-3)

Guidance literature:

With potassium fluoride; monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; palladium diacetate; In water; toluene; at 70 ℃; for 20h; Reagent/catalyst; Temperature; Inert atmosphere;

DOI:10.1021/jo401096u

upstream raw materials:

3-chloro-4,6-diphenyl pyridazine

(2RS,3SR)-4-chloro-2,3-epoxy-1,3-diphenyl-butan-1-one

(Z)-4-bromo-2,3-epoxy-1,3-diphenyl-1-butanone

3-phenyl-[1,2,4,5]tetrazine