1,2-Di-propionylaminobenzene

Base Information

• Chemical Name: 1,2-Di-propionylaminobenzene
• CAS No.: 10268-76-5
• Molecular Formula: C12H16N2O2
• Molecular Weight: 220.271
• DSSTox Substance ID: DTXSID10351257
• Nikkaji Number: J659.702E
• Wikidata: Q82127522
• Mol file: 10268-76-5.mol

Synonyms:N,N'-benzene-1,2-diyldipropanamide;1,2-di-propionylaminobenzene;10268-76-5;Propanamide, N,N'-1,2-phenylenebis-;1,2-dipropionylaminobenzene;Cambridge id 6986403;Oprea1_590827;Oprea1_733540;SCHEMBL8619629;DTXSID10351257;N,N'-1,2-phenylenedipropanamide;STK005678;AKOS002377498;N,N'-(1,2-Phenylene)bis(propanamide);N-(2-PROPANAMIDOPHENYL)PROPANAMIDE;SR-01000248140;SR-01000248140-1

Chemical Property of 1,2-Di-propionylaminobenzene

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 220.121177757
• Heavy Atom Count: 16
• Complexity: 227

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)NC1=CC=CC=C1NC(=O)CC

Technology Process of 1,2-Di-propionylaminobenzene

There total 6 articles about 1,2-Di-propionylaminobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

propionic acid anhydride (123-62-6) + 1,2-diamino-benzene (95-54-5) → N-(2-propionyllamino-phenyl)-propionamide (10268-76-5)

Guidance literature:

With sodium dodecyl-sulfate; In water;

DOI:10.1002/ejoc.200300620

Reference yield: 80.1%

1,2-diamino-benzene (95-54-5) → N-(2-propionyllamino-phenyl)-propionamide (10268-76-5)

Guidance literature:

In pyridine; propionic acid anhydride;

Reference yield: 80.0%

5-ethoxycarbonyl-6-methyl-1,3-dipropionyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one + N-(2-aminophenyl)propionamide (10268-79-8) → N-(2-propionyllamino-phenyl)-propionamide (10268-76-5)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tet.2009.10.037

upstream raw materials:

benzoimidazole

propionic acid anhydride

1,2-diamino-benzene

N-(2-aminophenyl)propionamide

Downstream raw materials:

1,2-bis[N-(4-chlorobutyl)-N-propionylamino]benzene