17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one

Base Information

Chemical Name:17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one
CAS No.:6173-64-4
Molecular Formula:C₂₃H₃₂O₅
Molecular Weight:388.504
Hs Code.:
Mol file:6173-64-4.mol

Synonyms:

Suppliers and Price of 17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
17,20:20,21-Bis(methylenedioxy)pregn-4-en-3-one
10mg
$ 165.00

Medical Isotopes, Inc.
17,20:20,21-Bis(methylenedioxy)pregn-4-en-3-one
25 mg
$ 800.00

Total 3 raw suppliers

Chemical Property of 17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one

Chemical Property:

Solubility.:DCM, Ethyl Acetate, Methanol

Purity/Quality:: 17,20:20,21-Bis(methylenedioxy)pregn-4-en-3-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 17,20:20,21-Bis(methylenedioxy)pregn-4-en-3-one is an intermediate in the synthesis of metabolites of Cortisol (H714615).

Technology Process of 17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one

There total 2 articles about 17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 152-58-9
Cortexolone

: 6173-64-4
17,20:20,21-bismethylenedioxy-4-pregnen-3-one

Guidance literature:: With hydrogenchloride; In chloroform; water; at 20 ℃; for 5h;
DOI:10.1016/j.steroids.2011.05.014

Reference yield:

: 6173-64-4,10007-30-4,10163-70-9,10163-71-0
Bis-methylendioxy-cortexolon

Guidance literature:: Pregnen-(4)-diol-(17α,21)-dion-(3,20), Formalin, konz. HCl in Chloroform;
DOI:10.1021/jo01351a064

Reference yield:

: 6173-64-4
17,20:20,21-bismethylenedioxy-4-pregnen-3-one

: 1415087-38-5
[2,2,α3,4,4-d5]-17,20;20,21-bismethylenedioxy-5α-pregnan-3β-yl p-toluenesulfonate

Guidance literature:: Multi-step reaction with 4 steps

1: lithium; ammonia / tetrahydrofuran / 0.33 h / 20 °C

2: [D]-sodium hydroxide; water-d2 / deuteromethanol; 1,4-dioxane / 22 h / 80 °C / Inert atmosphere; Cooling with ice

3: sodium borodeuteride / 0.67 h / 20 °C / Cooling with ice

4: pyridine / 24 h / Cooling with ice

With pyridine; sodium borodeuteride; [D]-sodium hydroxide; ammonia; water-d2; lithium; In tetrahydrofuran; 1,4-dioxane; deuteromethanol;
DOI:10.1016/j.steroids.2012.08.007