1,8-Octanediol, mono(4-methylbenzenesulfonate)

Base Information

• Chemical Name: 1,8-Octanediol, mono(4-methylbenzenesulfonate)
• CAS No.: 103010-10-2
• Molecular Formula: C15H24O4S
• Molecular Weight: 300.419
• Mol file: 103010-10-2.mol

Synonyms:8-hydroxy-1-tosyloxyoctane;Toluene-4-sulfonic acid 8-hydroxy-octyl ester;1,8-octanediol monotosylate;8-hydroxyoctyl 4-methylbenzenesulfonate;8-(4-Methylphenylsulfonyloxy)-1-octanol;

Chemical Property of 1,8-Octanediol, mono(4-methylbenzenesulfonate)

Chemical Property:

• PSA: 71.98000
• LogP: 4.11400

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,8-Octanediol, mono(4-methylbenzenesulfonate)

There total 8 articles about 1,8-Octanediol, mono(4-methylbenzenesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

8-(allyloxy)octyl tosylate → 8-(p-methylbenzenesulfonyloxy)-1-octanol (103010-10-2)

Guidance literature:

With Pd(OH)2/C; In isopropyl alcohol; for 1.5h; Reflux;

DOI:10.1016/j.tet.2012.09.016 DOI:10.1016/j.tet.2012.09.016

Reference yield: 80.0%

1-(4-Methylphenylsulfonyloxy)-8-(2-tetrahydropyranyloxy)octane (108535-80-4) → 8-(p-methylbenzenesulfonyloxy)-1-octanol (103010-10-2)

Guidance literature:

With titanium(III) chloride; In acetonitrile; at 20 ℃; for 6h;

DOI:10.1055/s-2004-834949

Reference yield: 75.0%

1,8-Octanediol (629-41-4) + Methyl p-tolyl sulfone (3185-99-7) → 8-(p-methylbenzenesulfonyloxy)-1-octanol (103010-10-2)

Guidance literature:

With triethylamine; In dichloromethane; water; at 20 ℃;

upstream raw materials:

1,8-Octanediol

p-toluenesulfonyl chloride

1-(4-Methylphenylsulfonyloxy)-8-(2-tetrahydropyranyloxy)octane

8-allyloxyoctan-1-ol

Downstream raw materials:

1-(4-Methylphenylsulfonyloxy)-8-(2-tetrahydropyranyloxy)octane

1-((1,1-Dimethylethyl)diphenylsilyloxy)-8-(4-methylphenylsulfonyloxy)octane

8-aminooctan-1-ol

8-((1,1-Dimethylethyl)diphenylsilyloxy)octan-1-ol