Technology Process of C35H34ClFN4O9S
There total 11 articles about C35H34ClFN4O9S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran;
at 20 ℃;
DOI:10.1021/jm3014844
- Guidance literature:
-
Multi-step reaction with 5 steps
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,4-dioxane / 80 °C / Inert atmosphere
2: potassium carbonate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
3: trifluoroacetic acid / 20 °C
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C
5: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 20 °C
With
tetrakis(triphenylphosphine) palladium(0); di-isopropyl azodicarboxylate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
1: |Suzuki Coupling;
DOI:10.1021/jm3014844
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium hydroxide / water; dimethyl sulfoxide / 1 h / 100 °C
2: zinc; ammonium chloride / water; acetone / 0.5 h / 20 °C
3: dicyclohexyl-carbodiimide; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C
4: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 20 °C
With
di-isopropyl azodicarboxylate; ammonium chloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; triphenylphosphine; potassium hydroxide; zinc;
In
tetrahydrofuran; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm3014844