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1089280-66-9

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1089280-66-9 Usage

General Description

1-Chloro-2-fluoro-4-methoxy-5-nitrobenzene is a chemical compound that is a derivative of benzene. It contains a chlorine atom, a fluorine atom, a methoxy group, and a nitro group attached to the benzene ring. 1-chloro-2-fluoro-4-methoxy-5-nitrobenzene is used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a building block in the production of dyes, pigments, and other specialty chemicals. The presence of the various functional groups in 1-chloro-2-fluoro-4-methoxy-5-nitrobenzene gives it a variety of reactivity and potential for use in various chemical processes. It is important to handle this compound with caution as it is potentially hazardous and should be used in accordance with proper safety procedures.

Check Digit Verification of cas no

The CAS Registry Mumber 1089280-66-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,9,2,8 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1089280-66:
(9*1)+(8*0)+(7*8)+(6*9)+(5*2)+(4*8)+(3*0)+(2*6)+(1*6)=179
179 % 10 = 9
So 1089280-66-9 is a valid CAS Registry Number.

1089280-66-9Relevant articles and documents

SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS

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Page/Page column 155, (2018/02/28)

Disclosed are compounds of the general formula (I), wherein R1-R3 are as defined herein, for use as MALT1 inhibitors in the treatment of autoimmune and inflammatory diseases or disorders. Methods of synthesizing the compounds are also disclosed. Also disc

Spiro aryl phosphorus oxide or sulfide

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Paragraph 0566; 0567; 0568; 0569; 0597; 0598; 0599; 0600, (2016/10/08)

The invention discloses a spiro aryl phosphorus oxide or sulfide as ALK inhibitor, and in particular discloses a compound shown in a formula (I) as an ALK inhibitor or a pharmaceutically acceptable salt thereof.

PHARMACEUTICAL COMPOUNDS

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Page/Page column 92, (2011/12/02)

The invention provides a compound of the formula (1): or a salt, N-oxide or tautomer thereof; wherein R1 is cyano or C1-4 alkyl; R2 is hydrogen or C1-4 alkyl; R3 is hydrogen or C1-4 alkyl; R4 and R5 are the same or different and each is selected from hydrogen, saturated C1-4 hydrocarbyl and saturated C1-4 hydrocarbyloxy; R6 and R7 are the same or different and each is selected from hydrogen, halogen, CN, C1-4 alkyl and C1-4 alkoxy wherein the C1-4 alkyl and C1-4 alkoxy are each optionally substituted with hydroxy, C1-2 alkoxy or by one or more flourine atoms; R8 is hydrogen or C1-4 alkyl; Q is an alkylene chain of 1 to 4 carbon atoms in length between the moiety Ar and the nitrogen atom N, wherein one or more of the 1 to 4 carbon atoms of the alkylene chain may optionally be substituted with one or two C1-4 alkyl groups, or wherein one carbon atom of the 1 to 4 carbon atoms of the alkylene chain may optionally be substituted with a group -CH2CH2- which together with the said one carbon atom forms a cyclopropyl group; m is 1, 2, 3 or 4; n is 0 or 1; and Ar is a monocyclic or bicyclic aryl or heteroaryl group of 5 to 10 ring members containing 0, 1, 2, 3 or 4 heteroatom ring members selected from O, N and S, the aryl or heteroaryl group being optionally substituted with one to four substituents R13 as defined in the claims. The compounds are inhibitors of Chk-1 kinase and are active against cancers.

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