ethyl β-anilinocinnamate

Base Information

• Chemical Name: ethyl β-anilinocinnamate
• CAS No.: 53256-22-7
• Molecular Formula: C₁₇H₁₇NO₂
• Molecular Weight: 267.327
• Mol file: 53256-22-7.mol

Synonyms:

Chemical Property of ethyl β-anilinocinnamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl β-anilinocinnamate

There total 32 articles about ethyl β-anilinocinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

aniline (62-53-3) + phenylpropynoic acid ethyl ester (2216-94-6) → ethyl (2Z)-3-phenyl-3-(phenylamino)prop-2-enoate (3556-76-1,124413-92-9,53256-22-7)

Guidance literature:

With potassium permanganate; 1,10-Phenanthroline; potassium hydrogencarbonate; copper dichloride; In benzene; at 120 ℃; for 24h; Reagent/catalyst; Solvent; Catalytic behavior; Schlenk technique; Sealed tube;

DOI:10.1055/s-0039-1690240

Reference yield: 96.0%

ethyl 3-oxo-3-phenylpropionate (94-02-0) + aniline (62-53-3) → ethyl β-anilinocinnamate (53256-22-7,124413-92-9,3556-76-1)

Guidance literature:

With 1,3,5-trichloro-2,4,6-triazine; at 25 ℃; for 0.166667h; Neat (no solvent);

DOI:10.1007/BF03245892

Reference yield: 93.0%

diazoacetic acid ethyl ester (623-73-4) + benzylidene phenylamine (538-51-2) → ethyl (2Z)-3-phenyl-3-(phenylamino)prop-2-enoate (3556-76-1,124413-92-9,53256-22-7) + ethyl trans-1,3-diphenylaziridine-2-carboxylate (20414-50-0,20414-52-2,49790-76-3) + (+/-)-cis-ethyl 1,3-diphenylaziridine-2-carboxylate + ethyl 3-(N-phenylamino)-2-phenylpropenoate (197007-02-6)

Guidance literature:

With boron trifluoride diethyl etherate; In hexane; for 15h; Yields of byproduct given; Ambient temperature;

DOI:10.1021/jo961391w

upstream raw materials:

diazoacetic acid ethyl ester

benzylidene phenylamine

(ethoxycarbonylmethyl)dimethylsulfonium bromide

ethyl 3-oxo-3-phenylpropionate

Downstream raw materials:

ethyl 4,5-dioxo-1,2-diphenyl-4,5-dihydro-1H-pyrrole-3-carboxylate

2-phenylquinoline-3-carboxylic acid ethyl ester

(S)-ethyl 3-phenyl-3-(phenylamino)propanoate

ethyl 3-(benzylamino)-3-phenylacrylate