7073-94-1

Basic information

• Product Name: 1-Bromo-2-(1-methylethyl)benzene
• Synonyms: 2-BROMOISOPROPYLBENZENE;2-BROMOCUMENE;2-ISOPROPYLBROMOBENZENE;1-bromo-2-propan-2-yl-benzene;1-BROMO-2-ISOPROPYLBENZENE;1-bromo-2-(1-methylethyl)benzene;o-bromocumene;benzene,1-bromo-2-(1-methylethyl)-
• CAS NO: 7073-94-1
• Molecular Formula: C₉H₁₁Br
• Molecular Weight: 199.09
• EINECS: 230-370-0
• Product Categories: Benzene derivates
• Mol File: 7073-94-1.mol
• Article Data: 16

Chemical Properties

• Melting Point: -58.8°C
• Boiling Point: 90 °C
• Flash Point: 90-92°C/15mm
• Appearance: /
• Density: 1.30
• Vapor Pressure: 0.282mmHg at 25°C
• Refractive Index: 1.5410
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Insoluble in water.
• BRN: 1857014
• CAS DataBase Reference: 1-Bromo-2-(1-methylethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-2-(1-methylethyl)benzene(7073-94-1)
• EPA Substance Registry System: 1-Bromo-2-(1-methylethyl)benzene(7073-94-1)

Safety Data

• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 7073-94-1(Hazardous Substances Data)

Usage

General Description

1-Bromo-2-(1-methylethyl)benzene, with the molecular formula C10H13Br, is an organic compound uniquely classified by its aromatic ring system bonded with a bromine atom and an isopropyl group. Being part of the family of benzene and substituted derivatives, it primarily finds applications in the production of other chemicals in various manufacturing settings. This whitish-yellow, crystalline substance is generally stable, non-reactive, and has a low evaporation rate. Detailed information about its toxicity, environmental impact, and safety measures is limited; hence, handling it with utmost care following the general safety protocols is recommended.

InChI:InChI=1/C9H11Br/c1-7(2)8-5-3-4-6-9(8)10/h3-7H,1-2H3

Upstream product

• 108-86-1 bromobenzene 
• 75-26-3 isopropyl bromide 
• 7073-70-3 1-bromo-2-isopropenylbenzene 
• 98-82-8 Isopropylbenzene 
• 643-28-7 2-isopropylaniline 
• 30951-66-7 2-(3-bromophenyl)-2-propanol 
• 88-69-7 2-(1-methylethyl)phenol 
• 57775-06-1 2-(2-bromophenyl)-2-methylpropanenitrile 

Downstream Products

• 527-84-4 2-methylisopropylbenzene 
• 101781-19-5 <3-Isopropyl-phenyl>-<4-dimethylamino-phenyl>-methanol 
• 89787-12-2 2-isopropylphenylboronic acid 
• 473918-47-7 1-(2-isopropylphenyl)indole 
• 64653-45-8 di(2-isopropylphenyl)amine 
• 643-28-7 2-isopropylaniline 
• 87768-45-4 N,N-diethyl-2-isopropylbenzamide 
• 256440-02-5 P(2-isopropylphenyl)2Br 
• 1004984-14-8 1-(2-isopropylphenyl)-2-methylnaphthalene 
• 1085850-81-2 diisopropyl(o-isopropylphenyl)phosphane 
• 108593-78-8 tetrakis(2-isopropylphenyl)stannane 
• 19099-54-8 2-isopropyliodobenzene 
• 577-55-9 1,2-diisopropylbenzene 
• 106989-32-6 2-(2-isopropylphenyl)propan-2-ol 

Relevant articles and documents

Catalytic Asymmetric Synthesis of Atropisomeric Quinolines through the Friedl?nder Reaction

A phosphoric acid catalyzed atroposelective Friedl?nder reaction was developed in which acetylacetone and a variety of 2′-substituted 2-Aminobenzophenones were successfully employed to give optically active biaryl quinolines in good yields and with high enantioselectivities.

On the ionizing properties of supercritical carbon dioxide: Uncatalyzed electrophilic bromination of aromatics

Supercritical carbon dioxide (scCO2), a solvent with a zero dipole moment, low dielectric constant, and no hydrogen bonding behavior, is a suitable medium to perform the uncatalyzed electrophilic bromination of weakly activated aromatics with no interference of radical pathways. The ability of scCO2 to promote these reactions matches those of strongly ionizing solvents such as aqueous acetic and trifluoroacetic acids. Conversely, carbon tetrachloride, with similar polarity parameters to scCO2, leads exclusively to side chain functionalization. The strong quadrupole moment, and the acidic, but non basic, Lewis character of carbon dioxide, are proposed as key factors for the singular performance of scCO2 in reactions involving highly polar and ionic intermediates.

Bromination of alkylbenzenes in 1-butyl-3-methylimidazolium bromide and its dibromide complex

Alkylbenzenes were subjected to bromination with molecular bromine using 1-butyl-3-methylimidazolium bromide as solvent. A complex of 1-butyl-3-methylimidazolium bromide with bromine was synthesized. It ensured bromination of alkylbenzenes with no bromine and solvent. The results of bromination in binary solvents and ionic liquids, 1-butyl-3-methylimidazolium bromide and tribromide were compared. The bromination of ethylbenzene with 1-butyl-3-methylimidazolium tribromide was accompanied by formation of a considerable amount of α-bromoethylbenzene, which is not typical of electrophilic aromatic substitution process.