3,4,6-tri-O-benzoyl-1,2-O-cholesterylorthobenzoyl-α-D-glucopyranose

Base Information

• Chemical Name: 3,4,6-tri-O-benzoyl-1,2-O-cholesterylorthobenzoyl-α-D-glucopyranose
• CAS No.: 100102-45-2
• Molecular Formula: C₆₁H₇₂O₁₀
• Molecular Weight: 965.237
• Mol file: 100102-45-2.mol

Synonyms:

Chemical Property of 3,4,6-tri-O-benzoyl-1,2-O-cholesterylorthobenzoyl-α-D-glucopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,6-tri-O-benzoyl-1,2-O-cholesterylorthobenzoyl-α-D-glucopyranose

There total 2 articles about 3,4,6-tri-O-benzoyl-1,2-O-cholesterylorthobenzoyl-α-D-glucopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2,3,4,6-tetra-O-benzoylglucosyl bromide (14218-11-2) + cholesterol (57-88-5) → 3,4,6-Tri-O-benzoyl-1,2-O-<α-(5-cholesten-3β-yloxy)benzyliden>-α-D-glucopyranose (100102-45-2) + (5-Cholesten-3β-yl)-2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosid (66252-72-0)

Guidance literature:

With 2,4,6-trimethyl-pyridine; silver trifluoromethanesulfonate; In dichloromethane; 1.) -30 deg C, 30 min.; 2.) 15 h, room temp.;

DOI:10.1002/jlac.198619860411

Reference yield:

2,3,4,6-tetra-O-benzoylglucosyl bromide (14218-11-2) + cholesterol (57-88-5,474-77-1,14868-17-8,23820-70-4,34026-89-6,57759-45-2,71869-93-7,121155-47-3,138456-89-0) → 3,4,6-tri-O-benzoyl-1,2-O-cholesterylorthobenzoyl-α-D-glucopyranose (100102-45-2,132016-05-8)

Guidance literature:

With 4 A molecular sieve; tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 40 ℃; for 20h; under 6000480 Torr; Yield given;

DOI:10.1246/cl.1990.2099

upstream raw materials:

2,3,4,6-tetra-O-benzoylglucosyl bromide

cholesterol

cholesterol

Refernces

• 1、 Harreus,Kunz. "Stereoselective glycosylation of steroid alcohols using 2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide (Pivalobromoglucose) and 2,3,4,6-tetra-O-(o-toluoyl)-α-D-glucopyranosyl bromide". . p. 717 - 730. Retrieved 2007/10/02.