methoxy(oxo)acetic acid

Base Information

• Chemical Name: methoxy(oxo)acetic acid
• CAS No.: 10304-09-3
• Molecular Formula: C3H4 O4 . K
• Molecular Weight: 142.153
• Mol file: 10304-09-3.mol

Synonyms:Ethanedioicacid, monomethyl ester, potassium salt (9CI); Oxalic acid, methyl ester,potassium salt (7CI,8CI); Monomethyl oxalate potassium salt; Potassium methyloxalate

Chemical Property of methoxy(oxo)acetic acid

Chemical Property:

• Vapor Pressure: 0.209mmHg at 25°C
• Boiling Point: 192.9°C at 760 mmHg
• Flash Point: 88.9°C
• PSA: 63.60000
• Density: 1.366g/cm³
• LogP: -0.75600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methoxy(oxo)acetic acid

There total 1 articles about methoxy(oxo)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Dimethyl oxalate (553-90-2) → potassium oxalate monomethyl ester (10304-09-3)

Guidance literature:

With potassium acetate; In methanol; water; at 80 ℃; for 3h;

Reference yield: 75.0%

potassium oxalate monomethyl ester (10304-09-3) + 4-bromo-<2,3,5,6-2H4>anisole (152404-45-0) → C9H6(2)H4O3

Guidance literature:

With 1,3-bis-(diphenylphosphino)propane; palladium dichloride; In 1-methyl-pyrrolidin-2-one; at 150 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.0c04139

Reference yield: 74.0%

triphenylplumbyl hydroxide (894-08-6) + potassium oxalate monomethyl ester (10304-09-3) → (C6H5)3PbO2CCO2CH3 (107399-19-9)

Guidance literature:

With methanol; In methanol; HO2CCO2CH3 prepared in situ from potassium salt in methanol, pptd. at room temp. by equimolar amount of R3MOH; suspn. in CH3OH warmed, solvent vol. reduced; elem. anal.;

DOI:10.1016/S0022-328X(00)98928-9

upstream raw materials:

Dimethyl oxalate

Downstream raw materials:

methoxalic anhydride

2‐benzyl‐3‐methylnaphthalene‐1,4‐dione

(C₆H₅)3PbO₂CCO₂CH₃

(C₆H₅)3SnO₂CCO₂CH₃

Refernces

• 1、 -. "Preparation method and application of D-dencichine". Paragraph 0051. . Retrieved 2016/10/17.
• 2、 -. "METHODS OF NAD+-DEPENDENT DEACETYLASE INHIBITORS". Page/Page column 25-26. . Retrieved 2008/06/13.