3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile

Base Information

• Chemical Name: 3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile
• CAS No.: 187545-98-8
• Molecular Formula: C₂₆H₁₇ClN₆OSe
• Molecular Weight: 543.874
• Mol file: 187545-98-8.mol

Synonyms:

Chemical Property of 3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile

There total 5 articles about 3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-chlorobenzenediazonium chloride (2028-74-2) + 5-Phenyl-3-(2-selenocyanato-acetyl)-1-p-tolyl-1H-pyrazole-4-carbonitrile (187545-89-7) → 3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile (187545-98-8)

Guidance literature:

With sodium acetate; In ethanol; at 0 - 5 ℃; for 3h; Yield given;

DOI:10.1002/jccs.199600072

Reference yield:

3-bromoacetyl-5-phenyl-1-p-tolylpyrazole-4-carbonitrile (174906-55-9) → 3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile (187545-98-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / ethanol / 0.5 h / Ambient temperature

2: sodium acetate / ethanol / 3 h / 0 - 5 °C

With sodium acetate; In ethanol;

DOI:10.1002/jccs.199600072

Reference yield:

acetic acid-(4-chloro-N-nitroso-anilide) (13014-92-1) → 3-[4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazole-2-carbonyl]-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile (187545-98-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / ethanol / 2 h / Ambient temperature

2: ethanol / 4 h / Ambient temperature

In ethanol;

DOI:10.1002/jccs.199600072

upstream raw materials:

p-chlorobenzenediazonium chloride

5-Phenyl-3-(2-selenocyanato-acetyl)-1-p-tolyl-1H-pyrazole-4-carbonitrile

potassium selenocyanate

acetic acid-(4-chloro-N-nitroso-anilide)