2,3-Dimethyl-4-phenylquinoline

Base Information

• Chemical Name: 2,3-Dimethyl-4-phenylquinoline
• CAS No.: 10352-65-5
• Molecular Formula: C17H15N
• Molecular Weight: 233.313
• DSSTox Substance ID: DTXSID80556459
• Nikkaji Number: J2.269.868K
• Wikidata: Q82438014
• Mol file: 10352-65-5.mol

Synonyms:2,3-Dimethyl-4-phenylquinoline;10352-65-5;DTXSID80556459

Chemical Property of 2,3-Dimethyl-4-phenylquinoline

Chemical Property:

• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 233.120449483
• Heavy Atom Count: 18
• Complexity: 269

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C2=CC=CC=C2N=C1C)C3=CC=CC=C3

Technology Process of 2,3-Dimethyl-4-phenylquinoline

There total 8 articles about 2,3-Dimethyl-4-phenylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

acetone (67-64-1) + (2-aminophenyl)(phenyl)methanone (2835-77-0) → 2,3-dimethyl-4-phenylquinoline (10352-65-5)

Guidance literature:

With o-benzenedisulfonimide; at 80 ℃; for 28h; Neat (no solvent);

DOI:10.1016/j.tetlet.2010.02.139

Reference yield: 85.0%

butanone (78-93-3) + (2-aminophenyl)(phenyl)methanone (2835-77-0) → 2,3-dimethyl-4-phenylquinoline (10352-65-5)

Guidance literature:

With 4-nitro-1,2-benzenedisulfonimide; at 80 ℃; for 12h;

DOI:10.1016/j.tet.2013.02.053

Reference yield: 75.0%

1-(2-aminophenyl)-2-methyl-1-phenylbut-3-en-1-ol (1004545-89-4) → 2,3-dimethyl-4-phenylquinoline (10352-65-5)

Guidance literature:

With 1,10-Phenanthroline; air; palladium diacetate; In methanol; at 40 ℃; for 36h; under 760.051 Torr;

DOI:10.1021/ol702153x

upstream raw materials:

butanone

(2-aminophenyl)(phenyl)methanone

1-(2-aminophenyl)-2-methyl-1-phenylbut-3-en-1-ol

acetone

Downstream raw materials:

2-(3-methyl-4-phenylquinolyliden-2-yl)-1-phenylethanone