(E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol

Base Information

• Chemical Name: (E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol
• CAS No.: 863310-61-6
• Molecular Formula: C₃₆H₃₂O₅
• Molecular Weight: 544.647
• Mol file: 863310-61-6.mol

Synonyms:

Chemical Property of (E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol

There total 5 articles about (E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(3,5-bis-benzyloxy-phenyl)-7-hydroxy-chromen-2-one → (E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol (863310-61-6)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / acetone

2: LAH; AlCl₃ / diethyl ether; tetrahydrofuran / 1.5 h

With potassium carbonate; lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; diethyl ether; acetone;

DOI:10.3987/COM-05-10424

Reference yield:

3,5-dibenzyloxyphenylacetic acid (2732-96-9) → (E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol (863310-61-6)

Guidance literature:

Multi-step reaction with 3 steps

1: KOAc / acetic anhydride / 10 h / 150 °C

2: K₂CO₃ / acetone

3: LAH; AlCl₃ / diethyl ether; tetrahydrofuran / 1.5 h

With potassium acetate; potassium carbonate; lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; diethyl ether; acetic anhydride; acetone;

DOI:10.3987/COM-05-10424

Reference yield:

benzyl bromide (100-39-0) → (E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol (863310-61-6)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / acetone

2: LAH; AlCl₃ / diethyl ether; tetrahydrofuran / 1.5 h

With potassium carbonate; lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; diethyl ether; acetone;

DOI:10.3987/COM-05-10424

upstream raw materials:

3-(3,5-dibenzyloxyphenyl)-7-benzyloxy-2H-1-benzopyran-2-one

3,5-dibenzyloxyphenylacetic acid

benzyl bromide

2,4-Dihydroxybenzaldehyde

Downstream raw materials:

2-(3,5-dibenzyloxyphenyl)-6-benzyloxybenzofuran

2,2'-oxybis[3-(3,5-dibenzyloxyphenyl)-6-benzyloxy-2H-1-benzopyran]

moracin M