C₁₂₃H₁₅₀N₁₄O₂₁

Base Information

• Chemical Name: C₁₂₃H₁₅₀N₁₄O₂₁
• CAS No.: 1139906-54-9
• Molecular Formula: C₁₂₃H₁₅₀N₁₄O₂₁
• Molecular Weight: 2160.63
• Mol file: 1139906-54-9.mol

Synonyms:

Chemical Property of C₁₂₃H₁₅₀N₁₄O₂₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂₃H₁₅₀N₁₄O₂₁

There total 1 articles about C₁₂₃H₁₅₀N₁₄O₂₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Val-OH (68858-20-8) + Fmoc-Leu-OH (35661-60-0) + Fmoc-Pro-OH (71989-31-6) + Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) + L-Asn(Trt) (132388-59-1) + Fmoc-L-Gln(Trt)-OH (132327-80-1,200623-62-7) + Fmoc-D-Phe-OH (86123-10-6) + Fmoc-Orn(Boc)-OH (109425-55-0,118476-89-4) + Fmoc-Phe-ONa → C123H150N14O21 (1139906-54-9)

Guidance literature:

Fmoc-Phe-ONa; With 2-chlorotrityl resin; at 20 ℃; for 2h; Automated synthesizer; solid phase reaction;

With piperidine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 2h; Automated synthesizer; solid phase reaction;

Fmoc-Val-OH; Fmoc-Leu-OH; Fmoc-Pro-OH; Fmoc-Tyr(tBu)-OH; L-Asn(Trt); Fmoc-L-Gln(Trt)-OH; Fmoc-D-Phe-OH; Fmoc-Orn(Boc)-OH; Further stages;

DOI:10.1021/jm801577r

Reference yield:

C123H150N14O21 (1139906-54-9) → C123H148N14O20 (1139906-60-7)

Guidance literature:

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In dichloromethane; for 2h;

DOI:10.1021/jm801577r

upstream raw materials:

Fmoc-Val-OH

Fmoc-Leu-OH

Fmoc-Pro-OH

Fmoc-Tyr(tBu)-OH

Downstream raw materials:

C₁₂₃H₁₄₈N₁₄O₂₀

Refernces