C₂₈H₂₂BrN₂P

Base Information

• Chemical Name: C₂₈H₂₂BrN₂P
• CAS No.: 350599-45-0
• Molecular Formula: C₂₈H₂₂BrN₂P
• Molecular Weight: 497.374
• Mol file: 350599-45-0.mol

Synonyms:

Chemical Property of C₂₈H₂₂BrN₂P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₂BrN₂P

There total 3 articles about C₂₈H₂₂BrN₂P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

triphenylphosphine (603-35-0) + 4-azido-2-bromo-8-methylquinoline (350599-40-5) → C28H22BrN2P (350599-45-0)

Guidance literature:

In benzene; for 3h; Heating;

DOI:10.1080/10426500008082406

Reference yield:

4-hydroxy-8-methyl-1,2-dihydroquinolin-2-one (1677-42-5) → C28H22BrN2P (350599-45-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 23 percent / PBr₅ / 1 h / Heating

2: 78 percent / NaN₃ / dimethylformamide / 1 h / Heating

3: 85 percent / benzene / 3 h / Heating

With sodium azide; phosphorus pentabromide; In N,N-dimethyl-formamide; benzene;

DOI:10.1080/10426500008082406

Reference yield:

2,4-dibromo-8-methylquinoline (260972-99-4) → C28H22BrN2P (350599-45-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / NaN₃ / dimethylformamide / 1 h / Heating

2: 85 percent / benzene / 3 h / Heating

With sodium azide; In N,N-dimethyl-formamide; benzene;

DOI:10.1080/10426500008082406

upstream raw materials:

triphenylphosphine

4-azido-2-bromo-8-methylquinoline

4-hydroxy-8-methyl-1,2-dihydroquinolin-2-one

2,4-dibromo-8-methylquinoline